Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"stable isotope tracer"”.
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Gluconeogenesis as a system : development of in vivo flux analysis of hepatic glucose production in Type 2 Diabetes
… observed in diabetic patients. We have developed stable isotope tracer methods to reconstruct hepatic glucose production fluxes by infusion of [13C, 2H]-glycerol and mass spectrometry analysis of plasma metabolites. Using this methodology we observe physiologic changes in liver cell lines and …
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The role of denitrification in the nitrogen cycle of New England salt marshes
… of nitrogen gas (N₂ fluxes and a ¹⁵N stable isotope tracer to determine the contribution of denitrification to salt marsh sediment N cycling. Denitrification in salt marsh tidal creekbottoms is a major sink for groundwater nitrate of terrestrial origin. I studied creekbottom …
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The Mitochondrial Fusion Protein, Optic Atrophy 1 (OPA1), Alters Cellular Metabolism to Support Cancer Cell Viability
… To investigate nutrient usage, we performed stable isotope tracer analyses using [13C5]- and [15N2]-glutamine, which revealed increased incorporation into amino acid derivatives, TCA cycle, and pyrimidine intermediates. To confirm reprogramming events, we assessed gene expression patterns and …
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The role of denitrification in the nitrogen cycle of New England salt marshes
… of nitrogen gas (N2) fluxes and a 15N stable isotope tracer to determine the contribution of denitrification to salt marsh sediment N cycling. Denitrification in salt marsh tidal creekbottoms is a major sink for groundwater nitrate of terrestrial origin. I studied creekbottom …
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Quantitative trait loci (QTL) for metabolite accumulation and metabolic regulation : metabolite profiling of interspecific crosses of tomato
… of metabolic profiling of natural variation, stable isotope tracer experiments and reverse genetic experimentation.
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Developing a stable isotope approach to trace the sources and metabolism of phosphorus in freshwaters
The oxygen isotope ratio of dissolved inorganic phosphate (δ18Op) represents a novel and potentially powerful stable isotope tracer for biogeochemical research. Analysis of δ18Op may offer new insights into the relative importance of different sources of phosphorus within natural ecosystems. Due to …
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Short-term dynamics of nano- and picoplankton in the southern Benguela upwelling system
… from three depths at a single station. Using stable isotope tracer and flow cytometry analyses it was determined that primary productivity was supported by regenerated production and that nano-picoplankton were responsible for up to 90% of the net primary production, with nanoeukaryotes and …
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Examining cancer metabolism in vivo
… the metabolic fate of any radioactive or stable-isotope tracer in tumors and tissues (2) strategies to create stable-isotope macromolecular (protein) tracers (3) a plasmapheresis strategy to deliver labeled protein in vivo (4) qualitative and quantitative methods to define kinetics of …
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Water Transport in the Vadose Zone and Hydrological Processes in Soil-Plant-Atmosphere Continuum (SPAC) in West Texas, USA
… of meteorological and soil water data, isotope tracers, numerical simulations, and remote sensing at a natural rangeland in West Texas. Possible sources of atmospheric moisture in west Texas were studied by the isotope tracers at different seasons and weather conditions. The summer …
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Effects of Leucine on Skeletal Muscle During 14 d Bed Rest in Middle-aged Adults
Aging is associated with a slow, progressive loss of muscle mass and strength. Mechanical unloading, such as that commonly experienced during hospitalization or spaceflight, results in a rapid loss of muscle mass and strength, particularly in older adults. Exercise, a potent countermeasure to such …