Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 29 for “"squamous cell carcinoma (SCC)"”.
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Sentinel node biopsy for the clinically N₊ & N₀ neck in squamous carcinoma of the head and neck
… Lymph Node Biopsy (SLNB) in head and neck squamous cell carcinoma (SCC); to determine its role in the approach to the clinically N+ neck in a Developing World setting; and its accuracy as an indicator of regional lymph node status in the clinically N neck.
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Should abdomino-perineal resection be considered when a defunctioning stoma is required for anal canal squamous cell carcinoma?
… (CMT) is the preferred treatment for anal squamous cell carcinoma, but a small subgroup needs a defunctioning colostomy with temporary intent. The aim of this study was to evaluate the stoma closure rate of patients needing defunctioning colostomies prior to CMT for anal squamous cell …
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Expression of E-cadherin and HGF in Hypopharyngeal Cancer
BACKGROUND AND OBJECTIVES: Head and neck squamous cell carcinoma (HNSCC) results from a multistep carcinogenesis process in which increasing degrees of mucosal changes and cellular atypia occur over large areas of epithelium. Hypopharyngeal squamous cell carcinoma(SCC) is well known as a aggressive …
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Apoptosis and Necroptosis in Basal Cell and Spinocellular Carcinoma of the Skin // Апоптоза и некроптоза при базоцелуларен и спиноцелуларен карцином на кожа
Skin carcinomas originating in the epidermis are of two main histological types: basal cell carcinoma (BCC) and spinocellular or squamous cell carcinoma (SCC). Since 2000, Bulgaria has seen a steady increase in the incidence and mortality of these neoplasms. Apoptosis is a process of programmed …
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Understanding the adhesome network in primary and metastatic cutaneous squamous cell carcinoma
Understanding how cancer cells survive, invade and migrate is of fundamental importance to the development of approaches to inhibit invasion and metastasis in patients. Proteins recruited at adhesion complexes, known as the adhesome, are involved in multiple mechanisms which control cancer cell …
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Molecular Classification of Basal Cell Carcinoma of Skin by Gene Expression Profiling
Non-melanoma skin cancers (NMSC) including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are more common kinds of skin cancer. Although these tumors share common pathological and clinical features, their similarity and heterogeneity at molecular levels are not fully elaborated yet. …
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Expression and Clinical Significance of the N-myc downstream regulated gene-1 in Hypopharyngeal Cancer
… induction of differentiation in various cancer cell lines. Ndrg-1 has been shown to be involved in tumor progression and metastasis in colon, prostate and breast cancer. However, the clinical significance of Ndrg-1 in hypopharyngeal cancer remains to be investigated, and we therefore examined …
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Role of CDC25 Phosphatases in Non-Melanoma Skin Cancer
… (UV). UV-induced DNA damage activates cell cycle checkpoints through a mechanism involving degradation of the cyclin dependent kinase activators, the cell division cycle 25 (CDC25) phosphatases, and also activates Erbb family members indirectly through reactive oxygen species …
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Primary cutaneous malignancies in the Northern Cape Province of South Africa: A retrospective histopathological review
… malignancies) were identified. Most common were Squamous Cell Carcinoma (SCC), Basal Cell Carcinoma (BCC), Kaposi Sarcoma (KS), Cutaneous Malignant Melanoma (CMM) and Basosquamous carcinoma. The odds of a White male developing SCC increased by 8% each year (OR: 1.08; CI: 1.01-1.15; p-value: …
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PARP inhibition in combination with radiation therapy for the treatment of feline oral squamous cell carcinoma
Feline oral squamous cell carcinoma (FOSCC) is a devastating tumor frequently palliated with radiation therapy (RT). Disappointingly, RT typically exerts marginal and transient tumor regression and new strategies to enhance RT efficacy are needed. Poly (ADP-ribose) polymerase (PARP) is a key …
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Human papillomaviruses in skin cancer and cervical cancer
… with an increased risk for development of squamous cell carcinoma (SCC) of the skin and that sun-exposure is a risk factor for cutaneous HPV infection. In the cervical cancer study we found in addition to the exposure to the oncogenic HPV type that is found in the cancer tissue, that …
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Novel Cutaneous Human Papillomaviruses and Biomarkers in the Skin Lesions
Non-melanoma skin cancer (NMSC), comprising of squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), is the most prevalent cancer amongst Caucasians. The main risk factor for the development of NMSC is UV-irradiation but human papillo-mavirus (HPV) might be a co-factor. We extended the …
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Human papillomaviruses of skin and genital lesions
… with non-melanoma skin lesions such as squamous cell carcinoma (SCC) and actinic keratosis (AK). We have analyzed skin and genital lesions for presence of HPV-DNA in order to search for unknown and known HPV types. As an attempt to identify women at risk for development of high-grade …
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Diversity of Skin Infections
… established link to infection. NMSC, including squamous cell carcinoma (SCC) and basal cell carcinoma, is the most common cancer among Caucasians. Ultraviolet radiation is an established risk factor. Human papillomaviruses (HPVs) have been established as the major cause of cervical cancer. Many …
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Oncostatin M Receptor Overexpression Promotes Tumour Progression in Squamous Cell Carcinoma, via Hypoxia Signalling and Multiple Effects on the Tumour Microenvironment
… virus (HPV) infection plays a role in cervical carcinoma initiation, but other genomic changes are needed for pre-malignant abnormalities to fully develop to cancer. This often happens through genomic instability caused by the virus oncoproteins. Several integrative genomic analysis studies have …
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Sino-Nasal Squamous Cell Carcinoma (SNSCC): a retrospective review of the treatment outcomes of patients treated at Groote Schuur Hospital, Cape Town, South Africa
… with radical and palliative intent for sinonasal squamous cell carcinoma (SNSCC). Methods: A retrospective review of medical records of all patients presenting to Cape Town's Groote Schuur Hospital between January 2003 and December 2013 was carried out. All patients with histologically proven …
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A review of the incidence and management of complications following malignant oesophageal stenting
… (73.4%) of palliative stents were placed for squamous cell carcinoma (SCC) with a total of 354 stent insertion attempts undertaken in 297 patients (49 requiring multiple stents). Three unsuccessful insertions and six incorrectly placed stents, all immediately addressed, equated to an immediate …
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Novel roles of ADF/cofilins in maintenance of homeostasis in normal and malignant epithelial cells
… of critical importance for a number of diverse cellular functions, including cell motility, endocytosis, cell division and transcription. Tight regulation of actin is critical for many aspects of cancer biology and in particular invasion and metastasis. ADF/cofilins are among the most important …
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Prevalence of ocular manifestations of HIV/AIDS among patients attending adult infectious disease centre(AIDC)of excellence at the University Teaching Hospital in Lusaka,Zambia
… Adult Infectious Disease Centre (AIDC) of excellence at UTH, Lusaka. HIV and AIDS related ocular manifestations may affect 50-75% of HIV positive patients at some point in the course of their illness. Zambia has an HIV prevalence rate of 13.0%. This study was conducted in order to establish …
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Prevalence of ocular manifestations of HIV/AIDS among patients attending adult infectious disease centre(AIDC)of excellence at the University Teaching Hospital in Lusaka,Zambia
… Adult Infectious Disease Centre (AIDC) of excellence at UTH, Lusaka. HIV and AIDS related ocular manifestations may affect 50-75% of HIV positive patients at some point in the course of their illness. Zambia has an HIV prevalence rate of 13.0%. This study was conducted in order to establish …
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