Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"sporadic Alzheimer's disease"”.
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Tau aggregation is heterogeneous across cases of sporadic Alzheimer's disease and is influenced by autophagy pathways in vitro
… of neurodegenerative conditions, including Alzheimer's disease. Understanding the kinetics of this aggregate build up, how it varies across patients, and how aggregation might be influenced by intracellular pathways is critical for both a deeper knowledge of these disorders as well as …
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Building a bridge between biophysics and neurobiology: A synergic approach to develop Alzheimer’s disease translational models and research tools
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder, accounting for 60-70% of dementia cases diagnosed worldwide. The impact of AD is rapidly increasing, with deaths more than doubling from 2000 to 2021. As populations age, especially in industrialized nations, the …
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Exploring SARM1 as a target to delay programmed axon degeneration
… exposure to neurotoxic compounds, and in diseases involving mitochondrial or metabolic dysfunction. There is increasing evidence that this pathway can be activated in human painful neuropathies and preclinical evidence suggests it is also active in neurodegenerative conditions, such as …