Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"split luciferase complementation assay"”.
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Insight into the Molecular Mechanisms of the Interactions and Functions of the Wheat Powdery Mildew AVRPM3 and SVRPM3$^t{a1/f1}$ Effectors and the Wheat NLR-Type Immune Receptor PM3b
… AVRPM3b2/c2 and we performed various interaction assays to try to confirm this. First, we tested PM3b and AVRPM3b2/c2 in a split-luciferase complementation assay, which gave negative results even though all proteins were present. We hypothesized that due to the large size of PM3b, there might be …
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Development of Hif-1Α/Hif-1Β Heterodimerization Inhibitors Using A Novel Bioluminescence Reporter Assay System For In Vitro High Throughput Screening and In Vivo Imaging
<p>Tumor growth often outpaces its vascularization, leading to development of a hypoxic tumor microenvironment. In response, an intracellular hypoxia survival pathway is initiated by heterodimerization of hypoxia-inducible factor (HIF)-1α and HIF-1β, which subsequently upregulates the expression of …