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Showing 1 to 3 of 3 for “"splicing regulatory elements"”.
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Identifying Splicing Regulatory Elements with de Bruijn Graphs
Splicing regulatory elements (SREs) are short, degenerate sequences on pre-mRNA molecules that enhance or inhibit the splicing process via the binding of splicing factors, proteins that regulate the functioning of the spliceosome. Existing methods for identifying SREs in a genome are either …
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Interpretable Computational Modeling of pre-mRNA Splicing for Multiple Eukaryotic Species
… steps in eukaryotic gene expression is pre-mRNA splicing, whereby intronic sequences are excised from immature pre-mRNA transcripts and the remaining exonic sequences are joined together. This process is catalyzed by the spliceosome, a large complex of proteins and RNAs. A variety of RNA sequence …
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Sequenziamento e Analisi Molecolare di Varianti Alleliche del Gene PRB1
… know that from PRB1, considering its allelic and splicing variants, are expressed six different proteins (Marconi et al., 2015). However, amongst the three allelic variants of this gene, the only of which we have the complete nucleotide sequence is the medium. Conversely, for the small and large …