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Showing 1 to 2 of 2 for “"splicing catalysis"”.
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The Role and Fate of Branch Site-U2 snRNA Interaction During Pre-mRNA Splicing
… dynamics underlying transitions during premRNA splicing, particularly during the catalytic phase, remain unclear despite our deep knowledge of spliceosome composition. The complex assembly phase that precedes catalysis, and the involvement of several motifs in multiple interactions along the …
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Structural studies of spliceosome assembly and catalysis
… and ligation of coding exons ––a process called splicing––is catalysed by a dynamic macromolecular machine called the spliceosome. The spliceosome assembles anew on precursor mRNA (pre-mRNA) from its component small nuclear ribonucleoproteins (snRNPs) and protein factors. A series of …