Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"spion"”.
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EXPANDING APPLICATIONS OF IRON OXIDE NANOPARTICLES BY SURFACE FUCNTIONALIZATION: FROM MAGNETIC RESONANCE IMAGING TO NANO-CATALYSIS
… of superparamagnetic iron oxide nanoparticles (SPIONs) in MR imaging and nanocatalysis via surface functionalization. A dopamine-based surface-functionalization strategy was established. The Simanek dendrons (G1 to G3), oligonucleotides and amino acids were loaded onto SPION surfaces via this …
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Developing a Microbubble-based Contrast Agent for X-ray Phase Contrast Imaging to Detect Neovasculature in Breast Cancer
… with superparamagnetic iron oxide nanoparticles (SPIONs). MBs were then immobilized in agar at three concentrations: 5×10⁷ (high), 5×10⁶ (moderate), and 5×10⁵ MBs/ml (low). MBs were imaged by synchrotron at the Canadian Light Source with In-line phase contrast imaging (PCI) and Multiple-image …
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Preparation of multifunctional nanoparticles using microfluidics
… superparamagnetic iron oxide nanoparticles (SPION) into LTSL was explored for their theranostic applications. Solvent compatibility of the microfluidic device was shown to be a limiting factor, which necessitated modifications of the preparation technique. Nanoprecipitation of SPION-loaded …
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Amphiphilic hyperbranched polyglycerols for industrial and biomedical applications
… of superparamagnetic iron oxide nanoparticle (SPION) clusters to serve as MRI contrast agents. The Janus HPGs (HPG-R) were synthesized by initiation of ring-opening multi-branching polymerization (ROMBP) of glycidol using resorcin[4]arene cavitand. The resorcin[4]arene, a cyclic macrocycle of …
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Investigating the Anti-Melanoma Activity of Combinatorial Paclitaxel and MEK Inhibitor
… superparamagnetic iron oxide nanoparticle (SPION), designed to accommodate the simultaneous encapsulation of two anti-melanoma compounds, with the addition of a melanoma cell-specific targeting moiety (α-MSH) attached to the surface of the nanoparticle (NP). The selection of PTX and SEL for …
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Polymer-mediated assembly of MRI contrast agents and their use in imaging of vascular defects
… of superparamagnetic iron oxide nanoparticle (SPION) contrast agents are investigated. Chapter 4 explores the use of hyperbranched polyglycerol (HPG) in assembling SPIONs in the form of spherical clusters. By controlling the cluster size and molecular architecture of the polymer coating, …
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Fabrication and characterization of a magnetic bacterial nanocellulose for neurovascular reconstruction of cerebral aneurysms
… superparamagnetic iron oxide nanoparticles (SPION) are formed inside the BNC by using ammonium hydroxide as precipitating agent. Different concentrations of Fe3+ and Fe2+iron salts were used for the synthesis of MBNC, and their effect on BNC permeability, porosity and magnetic saturation were …
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Making Nuclear Magnetic Hyperpolarization Practical through Storage in Disconnected Eigenstates
… of SuperParamagnetic Iron Oxide Nanoparticles (SPION). Contributions to the dephasing rate include the inhomogeneous field, the SPION magnetic field, and dephasing caused by collisions with the confining geometry. The sensitivity of either gas to SPION increases with increasing SPION …
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Self-assembly of anisotropic nanostructures and interferometric spectroscopy
… for assembling superparamagnetic nanoparticles (SPIONs) into structure-controlled 1D chains in a rotating magnetic field. The length of the SPION chains can be well described by an exponential distribution, as is also seen in SPION chains in a static field. In addition, the maximum chain length …
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Innovating surgery for oral squamous cell carcinoma with targeted fluorescent and magnetic tracers
… a superparamagnetic iron oxide nanoparticle (SPION) that has been engineered with mannose end targets for macrophage-specific binding to aid SLNB.
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A study of the vein copper mineralization of the Virgilina district, Virginia and North Carolina
… chalcopyrite, chalcocite/ djurleite, azurite, spion kopite, and yarrowite. This represents the first reported occurrence of djurleite, anilite, hessite, spionkopite, and yarrowite in the area. Lamellar intergrowths of anilite and djurleite on their close packed planes, myrmekitic intergrowths …
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New approaches to diagnostic imaging: Magnetic particle imaging for human functional neuroimaging and short mid-field MRI magnet design
… with superparamagnetic iron oxide nanoparticles (SPIONs), and by minimizing background signal levels which are not modulated by functional activity, it offers a promising alternative. However, there are no approved SPION tracers for human use that are well-suited to MPI, and we have little …
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MSC DERIVED EV IN REGENERATIVE MEDICINE
… and Supra Magnetic Iron Oxide Nanoparticles (SPION). These labelled cells and EV were then injected into a sheep stifle 1 week post creation of an OA model (meniscal transection model). These labelled cells and EV could then be seen within the knee for up to 4 weeks post injection, as …
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Fundamental studies and applications for the development of novel MRI contrast agents: Hyperpolarized xenon-129 and superparamagnetic iron oxide nanoparticles
… and superparamagnetic iron oxide nanoparticles (SPIONs). The largest `Achilles' Heel' of MR techniques is their inherent lack of detection sensitivity due to the exceedingly small magnitude of the nuclear spins, giving rise to small thermal polarizations. Chapter 2 reviews strategies for …
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NOVEL EXPERIMENTAL APPROACHES AND THEORETICAL MODELS FOR IMPROVING SENSITIVITY AND INFORMATION CONTENT OF NMR AND MRI SPECTROSCOPY
… in liquid-crystalline media. Finally the use of SPIONS--superparamagnetic iron oxide nanoparticles--as contrast agents is a relatively new approach to enhance information content in MRI studies; this is particularly true for SPIONs that have been surface-functionalized to achieve an …