Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"sphingolipid metabolite"”.
-
Sphingosine-1-phosphate in mast cell-mediated allergic responses
… likely to encounter the serum-borne bioactive sphingolipid metabolite, sphingosine-1-phosphate (S1P), during migration to target tissues. Mast cells developed from human cord blood-derived progenitors cultured with stem cell factor (SCF) alone express intragranular tryptase (MCT), the phenotype …
-
Receptor-mediated calcium entry in retinal amacrine cells
… containing different subunits. Recently, several sphingolipids have been demonstrated to play key roles in Ca<sup>2+</sup> mobilization in neurons. Sphingosine-1-phosphate is a sphingolipid metabolite that has been shown to activate a class of g protein-coupled receptors (S1PRs) in other cell …
-
The Role of Sphingosine Kinase 2 in Cell Growth and Apoptosis
Two isoforms of sphingosine kinase (SphK) catalyze the formation of sphingosine-1-phosphate (SIP). Whereas, SphKl stimulates cell growth and survival, it was found that when overexpressed in mouse NIH 3T3 fibroblasts SphK2 enhances caspase-dependent apoptosis in response to serum deprivation, …