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Showing 1 to 20 of 24 for “"spermiogenesis"”.
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Analysis of the role of the X/Y homologous gene family Xmr/Sly in murine spermiogenesis
… of a Yq-encoded multicopy genetic element (the ‘spermiogenesis factor’) is responsible for these phenotypes, and one potential candidate gene is Sly, a member of the Xlr superfamily. This family also includes Xmr, an X-linked multicopy gene found to be up-regulated (along with other X- and …
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A Tale of RNA Circles: Function of Circular RNAs in Reproduction
… and stop codons. Consequently, ~46% of these spermiogenesis-enriched circRNAs contain translatable CDS with an m6A-modified start codon located within their junction sites. The dynamic spatiotemporal production and subcytoplasmic compartmentalization, as well as the delicate regulation by m6A …
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The Reproductive Cycle of Sceloporus undulatus From Alabama Corresponding Plasma Steroid Levels and Comments on Reproductive Variation.
… In males, the height of the breeding season (spermiogenesis and spermiation) occurred from March to May. Testis mass declined during this time. Spermatozoa were present in the epididymides until July. In June and July, testis mass was minimal. A new spermatogenic cycle had begun by August. …
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Life history and physiological ecology of the lizard, Cordylus Giganteus
… Spermatogenesis commences in spring with peak spermiogenesis in autumn and testicular regression following in late autumn. Spermatozoa are stored in the epididymis and ductus deferens for seven to eight months. A bimodal plasma testosterone profile is reported, consistent with spermiogenesis in …
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Proteomic Profiling of Animal Models of Motor Neuron Disease and Muscular Dystrophy
… prognostics of motor neuron disease, impaired spermiogenesis and XQlinked muscular dystrophy.
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Mouse hybrid sterility genes linked to chromosome X
… harbors two additional factors responsible for spermiogenesis (Hstx1) and meiotic recombination rate (Meir1). In this work, we aimed to contribute to the identification of the Hstx2 candidate by...
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Characterization of the Genes Essential for Mouse Spermatogenesis
… through dramatic morphological changes termed spermiogenesis, during which: 1) the Golgi apparatus forms the acrosome, 2) nuclear chromatin undergoes compaction and condensation, 3) sperm tail is formed and 4) the excess cytoplasm of spermatid is eliminated. Given the complexity of …
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The Small GTPase Rheb Is Required for Spermatogenesis but not Oogenesis
… defect combined with subsequent abnormalities in spermiogenesis as evidenced by abnormal sperm morphology. In the female, however, germ-cell specific inactivation of Rheb was not associated with any discernible abnormality; these cKO mice were fertile with morphologically unremarkable ovaries, …
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Zur Transkriptions- und Translationskontrolle des Gens für Transitionsprotein
… the 3"UTRs of the late translated mRNAs during spermiogenesis. RNA-affinity chromatography was employed to show the specific binding of the cytoplasmic proteins to the in vitro transcribed 3"UTR of rat Tnp2.
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Sublethal effects of cadmium and diazinon on reproduction and larval behavior in zebrafish (Brachydanio rerio)
… male and female gonadal DHP concentrations, spermiogenesis, and altered larval swimming behavior. However, diazinon, at the sublethal concentrations I measured, did not impair reproduction. Larval swimming speeds in diazinon experiments appeared to follow an hormetic response: low doses …
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Analysis of target genes of the transcription factor CREM during mouse spermatogenesis
… expressed in postmeiotic germ cells during mouse spermiogenesis. Mutant male mice lacking CREM expression are sterile due to lack of maturation of the germ cells. The main task of thesis was to determine the CREMtau downstream target genes, i.e. the genes which are down regulated or not expressed …
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Mechanisms and consequences of DNA damage, response and apoptosis in spermatozoa.
… to an abortive topoisomerase-IIb activity during spermiogenesis. When comparing the DSB frequencies at the two most fragile genomic loci (fragile sites FRA3B, FRA16D) in human and murine spermatozoa with lymphocytes, significantly increased DSB levels were detected in spermatozoa in both species. …
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Mechanisms and consequences of DNA damage, response and apoptosis in spermatozoa.
… to an abortive topoisomerase-IIb activity during spermiogenesis. When comparing the DSB frequencies at the two most fragile genomic loci (fragile sites FRA3B, FRA16D) in human and murine spermatozoa with lymphocytes, significantly increased DSB levels were detected in spermatozoa in both species. …
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Regulating transcript fate through RNA elements in the 3' untranslated region
… are produced more than a month after birth. Spermiogenesis is the haploid stages of spermatogenesis; the first wave of this progress from round spermatids to elongated spermatids occurs roughly from post-natal day 21 to post-natal day 35. Tightly regulated temporal control of translation is …
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The Reproductive Physiology Of Brook Charr (salvelinus Fontinalis, Mitchill) From Neutral And Acidic Lakes In Northern Ontario
… acidic lakes initiated rapid spermatogenesis and spermiogenesis in July, one month later than charr from the neutral lakes. The rate of spermatogenesis increased in charr from acidic lakes in September, so by October, the quantity of spermatozoa in their testes was the same as in charr from …
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SPAG16 is a Bifunctional Gene Regulating Male Fertility
… to the condensation and elongation stage of spermiogenesis, the final specialization point in sperm development. The distinct localization of SPAG16S at this critical juncture, its interaction with discretely localized proteins at a critical temporal junction in spermatogenesis, and its …
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Zinc ion fluxes on the pathway to mammalian sperm fertilization competency
… spermatozoa from the round spermatid stage of spermiogenesis, to epididymal maturation, ejaculation, and up to 72 hours of liquid semen storage. Using image-based flow cytometry (IBFC), we identified four distinct sperm zinc signatures present in boar, bull, and human spermatozoa. The zinc …
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Apical Testis Structure and the Effects of Cadmium Treatment on Spermatogenesis in Drosophila
… assay to assess cadmium dosage effects on late spermiogenesis and a Live/Dead assay to assess mature sperm viability. The results of the DAPI assay and the Live/Dead assay both show a detrimental effect by CdCl <sub>2 </sub>on spermatogenesis in <em>D. melanogaster. </em>The goal of the DAPI …
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The Role of 5-Hydroxymethylcytosine in Genome Instability
… PRM2 is subject to proteolytic processing during spermiogenesis, in which the N-terminus is cleaved following DNA binding. Using a PRM2 N-terminus-deficient mouse model, I find that the cleaved region of PRM2 is essential for sperm genome stability and male fertility.
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