Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"spermatogonial stem cell"”.
-
Mechanism of Spermatogonial Stem Cell Regulation by ETV2
… is the process through which male germ cells give rise to spermatozoa. Spermatogenesis is initiated from spermatogonial stem cells (SSCs) which self-renew or differentiate to give rise to differentiated progenies of germ cells. Hence understanding of SSC biology is essential to …
-
Foxo Transcription Factors Control Spermatogonial Stem Cell Self-Renewal and the Initiation of Spermatogenesis
Spermatogonial stem cells (SSCs), as the foundation for spermatogenesis, must maintain a balance of both self-renewal and differentiation. Although several factors important for these processes have been identified, the fundamental mechanisms regulating SSC self-renewal and differentiation remain …
-
The role of UCH-L1 in mouse progenitor spermatogonia
… throughout the life of the adult male, the spermatogonial stem cell (SSC) population of the testis needs to achieve a balance between self-renewal and differentiation. The chemical, molecular and physical environment that supports this balance of fate decision is not completely understood. …
-
Engineering Matrix Properties for Stem Cell Culture and Gene Delivery
… tissues and frequently combines therapeutic cells, biomaterial scaffolds, and therapeutic molecules in efforts to do so. One of the primary considerations in such therapies is to orchestrate the interactions between these components to regulate the desired cellular responses. This thesis …
-
Impact of chemotherapy on the release and function of extracellular vesicles in the pre-pubertal testis
… in boys is reduced fertility, as it damages the spermatogonial stem cell (SSC) niche within the testis. This niche is essential for future fertility as these SSCs will differentiate into sperm following the onset of puberty. In post-pubertal males, this can be somewhat mitigated by the use of …
-
MicroRNA Expression Profiling of Multipotent Adult Germline Stem Cells
Es wurde gezeigt, dass Spermatogoniale Stammzellen (SSCs), die aus adulten Mäusehoden isoliert werden, durch Kulturbedingungen pluripotent werden und als "multipotent adult germline stem cells" (maGSCs) bezeichnet werden. Vor einiger Zeit wurde eine Gruppe nicht codierender RNAs identifiziert, die …