Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 38 for “"spermatocytes"”.
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Chromosome banding of German cockroach spermatocytes
A chromosome banding protocol for <u>Blattella germanica</u> speramtocytes was developed to reveal locations of constitutive heterochromatin (C-bands). Normality of the acid treatment used to denature basic (histone) proteins, temperature of the salt solution used to extract DNA from unhanded …
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Genetic Analysis of Crossover Defective Mouse Spermatocytes Reveals Discrete Crossover Precursor Intermediates
… result in aneuploidy. In humans, 1-8% of spermatocytes and 10-30% of oocytes are aneuploid, contributing to ~ 5% of clinically detected pregnancies with aneuploid embryos. With few exceptions, human aneuploidies are lethal; thus, aneuploidy is the leading genetic cause of infertility and …
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Higher Order Chromosome Organization and Recombination Dynamics of Meiotic Prophase I In Mouse Spermatocytes
<p>Meiotic recombination is required for parental chromosomes to find each other (pairing/synapsis) and to exchange genetic information thus allowing faithful segregation of chromosomes and the production of haploid gametes. At the start of meiotic prophase I, meiotic chromosomes organize into loop …
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Epic Search for the Perfect Partner: MutSgamma Promotes Efficient Meiotic Recombination and Homolog Pairing in Mouse Spermatocytes
… between more than two chromosomes). As such, spermatocytes from these mutants apoptose, and these mice are infertile. It has also been shown, both in budding yeast and in mouse, that mutations to the ATPase domain of MSH5 have similar defects. These mutants do not form crossovers and have …
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Characterizing the Effects of Jasplakinolide on Mesostoma Ehrenbergii Primary Spermatocytes to Study the Role of Actin during Chromosome Movement
My thesis investigated actins involvement in chromosome movement and function in the spindle. Generally, its thought that microtubules drive chromosome movement. However, when microtubules are depolymerized using nocodazole in Mesostoma ehrenbergii, chromosomes continue to move. To determine what …
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Gene expression changes during mammalian male meiotic initiation
… Type B spermatogonia, STRA8- preleptotene spermatocytes, loSTRA8 preleptotene spermatocytes, hiSTRA8 preleptotene spermatocytes, and leptotene spermatocytes. Following transcriptome sequencing, data analysis showed several different patterns of gene expression during meiotic initiation, but …
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ATM plays multiple roles in crossover regulation during mouse spermatogenesis
… of <em>Spo11</em> in <em>Atm<sup>-/-</sup></em> spermatocytes led to partial rescue with spermatocytes dying later in metaphase. Intriguingly, <em>Atm<sup>-/-</sup>Spo11<sup>+/-</sup></em> have more crossovers than wild type spermatocytes suggesting ATM may be involved in crossing over. To …
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Organ and primary culture of medaka (Oryzias latipes) testis: Test systems for the analysis of cell proliferation and differentiation
… period (17h), and spermatids that developed from spermatocytes were viable and motile. Primary cultures were characterized over a period of two days with respect to cell viability and the distribution of adherent and suspended cells. These two cell populations were maintained in dynamic …
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Anillin Stabilizes Membrane-cytoskeleton Interactions During Drosophila Male Germ Cell Cytokinesis
… required for cytokinesis in dividing Drosophila spermatocytes. In addition, spermatid individualization is defective in anillin-depleted cells, although similarities to another cytokinesis mutant, four wheel drive, suggest this may be a secondary effect of failed cytokinesis. Anillin, septins and …
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MET-2 and SET-25 have sexually dimorphic effects on chromosome structure in Caenorhabditis elegans
… diakinesis oocytes is significantly longer than spermatocytes. In addition, we found that mutations in different genes involved in histone post-translational modifications have distinct impacts on oocyte and spermatocyte bivalent length. A mutation of set-25, a histone methyltransferase …
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The involvement of ARF6 in rapid membrane recycling during Drosophila spermatocyte cytokinesis
… ARF6 is required for cytokinesis in Drosophila spermatocytes. The centralspindlin kinesin Pavarotti, identified as an ARF6 interactor in a Yeast-2-Hybrid assay, binds ARF6 in GST pulldowns, and interacts genetically with the arf6 mutant. ARF6 localizes to the plasma membrane and a population of …
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Possible Roles for Tropomyosin During Anaphase Chromosome Movement
… of the meiotic spindle of crane-fly primary spermatocytes. Overall, the data support the idea that tropomyosin is present in the spindle, where it may function during anaphase chromosome movement.
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A role for the Speedy gene family in the early stages of mammalian meiosis
… mouse SpeedyA, SpeedyB2, and SpeedyB3 mRNA in spermatocytes, the meiotic cells of the testis. Additionally, I found SpeedyA to be expressed in the embryonic ovary and its expression to be dependent on Stra8.
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Caractérisation de l'expression et de l'activité des facteurs SOX dans le testicule adulte de souris
… Sox5, Sox6 et Sox30 sont présents dans les spermatocytes et les spermatides." Mots clés : Testicule, Sertoli, Leydig, Cellules germnales, Transcription, SOX, SOX4, SOX8, spermatogénèse, Stéroïdogénèse.--Sommaire.
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A C. elegans histone methyltransferase promotes spermatocyte gene expression, spermatid production and fertility
… fertility through gene regulation in primary spermatocytes. SET-17 drives transcription of spermatocyte-specific genes from four genomic clusters to promote spermatid production. SET-1 7 is concentrated in stable, chromatin-associated nuclear foci at actively transcribed gene clusters, which …
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Pengaruh infusa daun murbei (Morus alba L.) terhadap gambaran histologi dan berat testis tikus putih (Rattus norvegicus) diabetes mellitus kronik
… the number of germ cells (spermatogonia, primary spermatocytes, secondary spermatocytes, spermatids and spermatozoa), Sertoli cells, the diameter of the seminiferous tubules, and testes weight. Data were analyzed with One Way ANOVA, if there is a very real difference then followed by further test …
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Chromosome evolution and mechanisms of speciation in the Anopheles gambiae complex
… meiotic division failed to produce primary spermatocytes and were accompanied with unpaired and insufficiently condensed chromosomes. As a result, primary spermatocytes undergo a mitosis-like anaphase division, producing nonmotile and malfunctional diploid sperm with two tails. However, …
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Localization studies of sister-chromatid cohesion proteins MEI-S332 and RAD21 in Drosophila
… its localization in early stages of meiosis in spermatocytes.
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Distortions of the genetic map of chromosome I in Caenorhabditis elegans
… The frequency of recombination in hermaphrodite spermatocytes was two-fold higher than that observed in oocytes and male spermatocytes . Thus, recombination frequencies appear to be a function of gonad physiology rather than sexual phenotype. To test this further, recombination was measured in …
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Characterization of the Genes Essential for Mouse Spermatogenesis
… spermatogonia through mitotic division. Primary spermatocytes produced from differentiated spermatogonia enter the prolonged prophase of meiosis during which DNA is exchanged by homologous recombination. Primary spermatocytes undergo two meiotic divisions to form haploid spermatids. Haploid …
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