Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 23 for “"species comparison"”.
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Computational Analysis of Gene Expression Regulation from Cross Species Comparison to Single Cell Resolution
… data sets are available from diverse species. This trend enables us to perform comparative transcriptome analysis that identifies conserved or diverged gene expression responses across species using transcriptome data. The goal of this dissertation is to develop and apply approaches of …
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Larval trematode populations and host-parasite interactions in Cerithidea Californica
… the fecundity of the parasitic trematode species in its gonad. Five species of trematodes are studied (Cloacitrema michiganensis, Euhaplorchis californiensis, Parorchis acanthus, Himasthia rhigedana, and Acanthoraryphium sp.). Their fecundity is determined by direct counts of rediae and …
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Computational genomics : mapping, comparison, and annotation of genomes
… information, and ultimately study, cross-species comparison, and annotation of finished genomic sequence. We present applications of computational techniques to the above areas: (1) In relation to the early stages of a genome project, we address physical mapping, and we present results on …
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Therapeutic Potential of Protein Kinases and Their Downstream Targets Following Traumatic Cervical Spinal Cord Injury
… cervical SCI. First, a comparative cross-species transcriptional and genomic analysis identified molecular pathways with great therapeutic potential and translational relevance. As these molecular targets were predominantly kinase-related, the subsequent experiments were aimed to assess …
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Adhesive and frictional tarsal pads in stick insects
… roles are understood, a comprehensive intra-species comparison of their structural, mechanical, and chemical characteristics has been missing. This thesis addresses these gaps by analysing and comparing the ultrastructure and mechanical properties of the arolium and euplantulae, as well as …
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Preparation and characterization of pentadentate Schiff base cobalt(II) complexes and their dioxygen adducts
… believed to involve both superoxo and unreacted species. Comparison of the structure of precursors to that of a dimeric peroxo adduct suggests a different mode of bonding than that which occurs in dioxygen complexes with other types of ligands. The significance of this is explored in terms of the …
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The dynamics and kinematics of bio-in swimming systems
… an animal's motion. We apply this method to species in both high and low Reynolds number environments to elucidate different phenomena, including chemotaxing and species comparison in spermatozoa, gait changes in eels (steady versus accelerating), kinematic responses to viscosity and …
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Impact of Weed Control and Fertilization on Growth of Eastern White, Loblolly, Shortleaf, and Virginia Pine Plantations in the Virginia Piedmont
The relative growth response of planted loblolly (Pinus taeda L.), shortleaf (Pinus echinata Mill.), Virginia (Pinus virginiana Mill.), and Eastern white (Pinus strobus L.) pines to intensive silvicultural practices such as woody competition control and fertilization in the Piedmont Province of …
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Change Detection Memory In Rhesus Monkeys and Humans
… order to directly compare VSTM between the two species and explore the possibility that direct species comparison might shed light on the fixed-capacity vs. continuous-resource models of VSTM. The comparative results suggest qualitatively similar VSTM for the two species through converging …
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Fine mapping studies of quantitative trait loci for baseline platelet count in mice and humans
… for platelet count was performed, and a cross-species comparison conducted to identify regions where human associations and murine linkage peaks might coincide. Although this association study did not unequivocally identify syntenic regions associated with platelet count in humans where linkage …
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ACME and SPLiT-seq: Quantitative and evolutionary single-cell transcriptomics in planarians
… single-cell atlases for the planarian species Schmidtea mediterranea and Dugesia japonica. Later, I use the same pipeline in a single-cell RNA interference study, in S. mediterranea, to describe and quantify the effects of the hnf4 knockdown at tissue-resolution. Our results reveal …
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Feto-placental vascular structure and function: comparison of within and between species variations
… This thesis is motivated by a need to understand species differences, as despite promising therapies for pregnancy complications in animal models, clinical effectiveness is limited due to differences in placental structure and function between species. The first aim was to quantify the vascular …
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Integration and analysis of protein evolutionary relationships and small molecule bioactivity data
… between homologous proteins within and across species. Potency differences between related proteins are a useful indicator of small molecule specificity. Specificity is an early milestone for most drug discovery projects as it allows for the manipulation of a desired process in a targeted …
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Transcriptomic Signatures of Projection Class Neurons for Vocal Control
… birds and five times in mammals. Vocal learning species exhibit an underlying convergence in brain circuitry, including a direct, forebrain-to-brainstem projection critical for the motor production of learned vocalizations. The remarkable convergence in fore brain vocal circuitry is associated …
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Quantifying the pro- and antimutagenic roles of DNA damage and repair
… in clinical oncology. Lastly, the cross-species comparison shows that the fundamental laws of mutagenesis are acting similarly across eukaryotic organisms reminding that many mutational processes fuelling tumorigenesis are not exclusive to cancer, but also drive variation and the …
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Genome-wide diversity assessment for genetic resource management of Eucalyptus dunnii, E. grandis, E. nitens and E. urophylla
The genus Eucalyptus with its over 900 species is a dominant genus of the Australian flora, many provide the foundation for closed forest habitats on the continent. In addition to its ecological significance, this genus is globally important as several species and interspecific hybrids are used in …
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Investigating Maladaptive Habit Formation and Threat Influences in Obsessive-Compulsive Disorder
… for the translational relevance of PIT between species. Rodent PIT studies reveal insights into the acquisition and consolidation of reward-based learning in humans, therefore a cross-species comparison to optimise the PIT procedure is a crucial consideration. To both improve the cross-species …
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Going through the motions : the impacts of frequent fires and grazing pressure on reproduction of Montane grassland birds
… and nesting success of several grassland bird species that breed in the high altitude grasslands of Wakkerstroom, South Africa. I established study plots in heavily grazed and annually burned, lightly grazed and annually burned, and lightly grazed and biennially burned plots. These represent …
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Mosquito Odorant Receptors: C-terminal Motifs, Subfamily Expansion, and Function
… blood from a variety of hosts many mosquito species show marked preferences for particular host species. Mosquitoes displaying preference for humans above bovines are more likely to be disease vectors. Therefore understanding the molecular basis of this preference is important for public …
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