Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"sonoporation"”.
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Biomedical ultrasonics, cavitation, and sonoporation
… treats biomedical ultrasonics, cavitation and sonoporation. Focussed ultrasound surgery can heat tissue to a temperature that causes protein denaturation and coagulative necrosis. For high-resolution focused ultrasound microsurgery, high working frequencies are necessary. We manufactured a …
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Microfluidic systems for cell transfection using sonoporation and electroporation
Studies into sonoporation and electroporation have grown rapidly in biotechnology and medicine in recent years. This research presents a microfluidic system for cell transfection using sonoporation and electroporation. This research has studied, designed, developed and tested the sonoporation …
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The Role of Ultrasound Contrast Agents in Producing Sonoporation
… elucidated the physical mechanism of sonoporation. Oscillation of UCAs near a cell produced microstreaming that resulted in shear stress on the cell membranes. This shear stress resulted in sonoporation, a permeability change that allowed for the uptake of macromolecules into the cells.
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Flow-Through Microfluidic Device for High-Efficiency Transfection of Mammalian Cells through Combined Microelectroporation and Sonoporation
… required for microelectroporation and micro-sonoporation in a flow-through fashion that allows for high throughput, high efficiency transfection of mammalian cells. During the design stage, we developed a low-cost, high-resolution polymer microfabrication technique termed laser stenciling. …
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Sonoptics : applications of light and sound in the context of biomedicine
… cells. This process is commonly referred to as 'sonoporation', and the enhanced uptake can be caused through the incident ultrasonic pressure fi eld causing radial oscillations (cavitation) in the microbubbles, amongst other possibilities. However, the mechanisms responsible for any resultant …
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Non-linear, non-spherical bubble dynamics near a two fluid interface
… procedures including laser ablation and sonoporation. A numerical investigation has been conducted to examine the essentially incompressible fluid dynamics of the exterior liquid layers, based on a boundary integral implementation coupled with the vortex ring toroidal bubble model [53]. …
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Ultrasound mediated Targeted Drug Delivery In Vitro: design, evaluation and application
… drug uptake is increased through heating and sonoporation processes. The release mechanisms from the carriers were also observed, validating the concept of USmTDD from CD-based carriers.<br/>
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Cell squeezing : a vector-free microfluidic platform for intracellular delivery of macromolecules
… Physical methods, such as electroporation and sonoporation, have been able to address some of the challenges with vector-based methods by providing a platform for physical disruption of the cell membrane. By eliminating the need for vector materials and circumventing the endocytotic pathway, …