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Showing 1 to 3 of 3 for “"somatic cell nuclear transfer (SCNT)"”.

  1. Involvement of mitochondrial transcription factor A (TFAM) in porcine gametogenesis and preimplantation embryo development

    … activated oocytes and zygotes reconstructed by somatic cell nuclear transfer (SCNT). Boar sperm TFAM was found to be posttranslationally modified by ubiquitination and relegated to sperm tail principal piece in fully differentiated spermatozoa. These data suggest that mitochondrial transcription …

    missouri Repository record for Involvement of mitochondrial transcription factor A (TFAM) in porcine gametogenesis and preimplantation embryo development (opens in a new tab)

  2. Quiescence induces epigenetic changes in bovine fibroblasts and improves their reprogramming into cloned embryos

    Cloning by somatic cell nuclear transfer (SCNT) forces cells to lose their lineage-specific epigenetic marks and become totipotent again. This reprogramming process often results in epigenetic and transcriptional aberrations that compromise development. Development rates after SCNT can thus serve …

    waikato-masters Repository record for Quiescence induces epigenetic changes in bovine fibroblasts and improves their reprogramming into cloned embryos (opens in a new tab)

  3. Effects of somatic cell nuclear transfer on transcripts related to IGF signaling, EGF signaling and cell adhesion during the peri-implantation period in cattle

    Up to 70% of somatic cell nuclear transfer (SCNT)–derived bovine pregnancies are lost during the peri-implantation period of gestation. Given the physiology of blastocyst implantation and clinico-pathological features that characterize SCNT pregnancies, we hypothesized that insulin-like growth …

    uiuc Repository record for Effects of somatic cell nuclear transfer on transcripts related to IGF signaling, EGF signaling and cell adhesion during the peri-implantation period in cattle (opens in a new tab)