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Showing 1 to 2 of 2 for “"somatic cell nuclear reprogramming"”.
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The role of transcription factors in somatic cell nuclear reprogramming by eggs and oocytes
Somatic cell nuclear reprogramming (SCNR) by eggs is a way to forcibly transform the nuclei of terminally differentiated somatic cells to an embryonic state and gain totipotency (Gurdon et al., 1958). Additionally, induced pluripotency is applied to transform identities of somatic cells to induced …
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Fusion of bovine fibroblasts to mouse embryonic stem cells: a model to study nuclear reprogramming
The cells from the inner cell mass (ICM) of an early embryo have the potential to differentiate into all the different cell types present in an adult organism. Cells from the ICM can be isolated and cultured in vitro, becoming embryonic stem cells (ESCs). ESCs have several properties that make them …