Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 102 for “"solid-state nuclear magnetic resonance"”.
-
Solid State Nuclear Magnetic Resonance of Quadrupolar Nuclei (Nmr)
Solid State Nuclear Magnetic Resonance has been used to study a variety of systems of geologic and chemical interest including feldspars, phyllosilicates, zeolites and aluminas. High magnetic field strengths (8.5 T) and Magic Angle Sample Spinning (MASS) yield high resolution spectra for …
-
Multinuclear Solid-State Nuclear Magnetic Resonance Spectroscopy of Microporous Materials
… information from other techniques such as solid-state NMR (SSNMR) spectroscopy. This thesis is focused on the study of two types of microporous materials, metal–organic frameworks (MOFs) and titanosilicates, by multinuclear SSNMR spectroscopy in combination with quantum chemical …
-
Solid-state nuclear magnetic resonance of rhodopsin and its photointermediates
… these mechanisms by means of low-temperature solid-state NMR<br/>is both subject and aim of this Ph.D. thesis. The issue of the energy storage has<br/>been investigated by a solid state magic angle spinning technique which combines<br/>modern symmetry-based recoupling techniques with in situ …
-
Solid-State Nuclear Magnetic Resonance Spectroscopy of Alpha-Synuclein Fibrils
Recent solid-state NMR (SSNMR) studies on protein systems such as beta-amyloid and the prion HET-s demonstrate the applicability of these techniques towards solving 3D structures of amyloid fibrils. Alpha-synuclein is a 140-residue protein that has been implicated in Parkinson's disease. Fibrils of …
-
Solid state nuclear magnetic resonance methodology for biomolecular structure determination
Several developments in solid state nuclear magnetic resonance (SSNMR) spectroscopy methods are presented. All studies are performed with magic angle spinning (MAS) and high-power proton decoupling, for optimal sensitivity and resolution. Chemical shift are assigned by multi-dimensional correlation …
-
Molecular and spin dynamics in solid state nuclear magnetic resonance spectroscopy
Nuclear Magnetic Resonance (NMR) spectroscopic data often involve spatial and spin dynamics and interference phenomena between the two. Experimental results are presented which demonstrate several of these phenomena and exploitation of these anomalies to acquire and improve knowledge regarding …
-
Structure and dynamics studies by solid-state nuclear magnetic resonance spectroscopy
… this work is the development of high resolution solid state 205T1 NMR techniques and their application to the elucidation of the mechanism and dynamics of ion exchange in biological solids. The thesis starts with a review of recent progress in solid state NMR spectroscopy. The importance of …
-
Dipolar recoupling and decoupling in solid state nuclear magnetic resonance spectroscopy
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1995.
-
Solid-State Nuclear Magnetic Resonance Studies of Quadrupolar Nuclei in Inorganic Systems (Nmr)
Solid-state nuclear magnetic resonance (NMR) has been used to study a variety of systems of chemical, physical, and geological interest, including zeolites, metasilicates, and semiconductors. Among the nuclei studied were $\sp $O, $\sp{27}$Al, $\sp{69}$Ga and $\sp{71}$Ga. The general motivations …
-
Solid-state nuclear magnetic resonance of quadrupolar nuclei with applications to biological solids
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1999.
-
Measurements of segmental order parameters and torsional angles in solid state nuclear magnetic resonance
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1998.
-
Advances in Sensitivity and Resolution of Solid State Nuclear Magnetic Resonance and Dynamic Nuclear Polarization
… such as x-ray crystallography and solution-state nuclear magnetic resonance (NMR) cannot provide atomic level resolution of insoluble, noncrystalline proteins. Such proteins include amyloid fibrils implicated in numerous neurodegenerative diseases. While solid state NMR using magic angle …
-
Spins, peptides, and Alzheimer's disease : solid-state nuclear magnetic resonance investigations of amyloid peptide conformation
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1996.
-
Applications of Solid State Nuclear Magnetic Resonance Spectroscopy as a Tool for Structure Based Drug Design
… and herbicidal activity. I have used solid state NMR spectroscopy as a tool to obtain structural information on the binding of inhibitors like bisphosphonates and phosphonosulfonates to their enzyme targets. Since bisphosphonates have been used primarily as osteoporosis drugs, I have …
-
Biomolecular Solid-State Nuclear Magnetic Resonance Methods for Spectral Assignment and High-Resolution Structure Determination of Proteins
Multidimensional solid-state nuclear magnetic resonance (SSNMR) experiments for the elucidation of structure in microcrystalline proteins are presented, utilizing the streptococcal beta-1 immunoglobulin binding domain of protein G (GB1) as a model protein. Complete 13C and 15N chemical shifts are …
-
Solid state nuclear magnetic resonance methodology and applications to structure determination of peptides, proteins and amyloid fibrils
… and applications of multidimensional solid-state nuclear magnetic resonance to biomolecular structure determination are presented. Studies are performed in uniformly 3C, 15N isotope labeled samples with magic-angle spinning for optimal resolution and sensitivity. Frequency selective …
-
Solid-state nuclear magnetic resonance investigations of the influenza M2 protein : structure and dynamics characterization of channel gating and conduction
Solid-state nuclear magnetic resonance (ssNMR) spectroscopy is a powerful technique that can be used to probe the structure and dynamics of biomolecules that are intractable to study by other structural biology methods. In this thesis, the mechanisms of conduction and gating are investigated in the …
Page 1 of 6