Global ETD Search
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Showing 1 to 3 of 3 for “"solid form screening"”.
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Microfluidic platforms for solid form screening of pharmaceutical parent compounds
Solid form screening and selection of pharmaceutical parent compounds (PCs) has been identified as a critical step in the early stages of drug development. A significant fraction of candidate PCs are rejected on account of poor physicochemical properties that affect their biopharmaceutical …
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Solvent compatible microfluidic platforms for solid form screening of pharmaceutical parent compounds
… of these compounds are typically determined by screening, crystallization, and subsequent analysis of various solid forms of a compound obtained. Currently the solid form screening process is performed by robotic platforms that require on the order of 0.5 g of material to screen 100 conditions. …
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Crystallization of active pharmaceutical ingredients using microfluidic platforms and meniscus-guided coating
… High throughput screens yield multiple solid forms of candidate drugs that are later characterized and prioritized for further development. Another focus within the pharmaceutical industry has been to improved manufacturing practices with continuous manufacturing and online monitoring …