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Showing 1 to 5 of 5 for “"sodium ion channel"”.
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Dielectric Relaxation Processes at Apical Membranes of Frog Skin: Changes of Capacitance and Sodium Ion Channel Density
… membranes and to determine whether vesicle fusion is the likely mechanism for the regulation of apical Na$\sp+$-channel density. Experiments were done in the presence of 100 $\mu$M amiloride and Na$\sp+$-free apical Ringer solution. This procedure reduced this epithelium to an electrical …
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Structural and functional role of the extracellular loops and C-terminal domain of the voltage-gated sodium ion channel
Voltage-gated sodium ion channels (Nav) are central to action potential initiation through regulating the entry of sodium ions (Na+) into excitable cells including cardiomyocytes and neurones. The α-subunit of Nav consists of four homologous domains (DI-DIV), each consisting of six transmembrane …
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Comparison of the sodium ion channel densities, the water flux changes, and the membrane capacitance changes in the pelvic and pectoral skin of the toad, Bufo woodhousei
… skin from the pelvic but not the pectoral region of the toad, Bufo woodhousei. The apical membrane capacitance (C{dollar}\sb{\rm a}{dollar}) of the cells in the stratum granulosum of neither skin region was changed by AVT treatment when an osmotic gradient was present across the tissue; Short …
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Analysis of Exome Sequencing in Hepatocellular Carcinoma
… any specific target genes is needed. The mutation of known oncogenes was found from previous sequencing studies. The samples from HCC and surrounding liver samples were dissected from twelve HCC patients to investigate the pattern of tumor heterogeneity and analyze by subgroups, to be used in …
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Identification of Residues Critical to Epithelial Sodium Channel Assembly
The Epithelial Sodium Channel (ENaC) is a major determinant in fine-tuning the volume and pressure of blood within the cardiovascular system. Understanding the regulation, structural assembly, and arrangement of ENaC is needed. This study describes a method for identifying residues that participate …