Global ETD Search
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Showing 1 to 4 of 4 for “"snoRNP"”.
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Sequence Dependence of the Folding of Kink-Turns in RNA
… the assembly of the biologically active box C/D snoRNP complex. Nevertheless, naturally occurring sequence modifications, such as N6-adenine methylation, can also alter the folding capability of kink-turns. A recently found example suggests that the naturally occurring N6-methyladenine …
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Oncogenic Pathways and Molecular Prognostics in Neuroblastoma
… microarrays we identify a group of proteins (snoRNPs) whose expression correlates with poor prognosis. We futher show that the snoRNPs are involved in regulation of telomerase activity in neuroblastoma cells. Upon snoRNP knockdown there is an observed increase in anaphase bridge fromation, …
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Nucleolar Stress Due to Depletion of Nopp140 in Drosophila melanogaster
… appeared intact in Nopp140-/- cells, the C/D snoRNP methyl-transferase, fibrillarin, redistributed to the nucleoplasm in variable amounts; RT-PCRs showed that 2’-O-methylation of rRNA in Nopp140-/- cells was reduced. Ultra structural analysis showed that Nopp140-/- cells were deficient in …