Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"smooth muscle contractility"”.
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Differentiation and contractility of colon smooth muscle under normal and diabetic conditions
Intestinal smooth muscle development involves complex transcriptional regulation leading to cell differentiation of the circular, longitudinal and muscularis mucosae layers. Differentiated intestinal smooth muscle cells express high levels of smooth muscle-specific contractile and regulatory …
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Serum response factor-dependent regulation of smooth muscle gene transcription
… the changes in the structure and function of smooth muscle cells. During the pathogenesis of these diseases, smooth muscle cells have a marked alteration in the expression of many smooth muscle-specific genes and smooth muscle cells undergo a phenotypic switch from the …
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Establishing a Model of Organ regeneration in the Adult Mammal: Age Dependence and the Utility of Non-Invasive Imaging
… including nerves, vessels, urothelium, and smooth muscle. Despite subtle differences in shape and contractility, bladders displayed a normal low pressure, high capacity function, and were able to empty completely 8 weeks after cystectomy. Computed tomography imaging corroborated this …
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Differentially expressed genes in aortic cells from atherosclerosis-resistant and atherosclerosis-susceptible pigeons
… Carneau (WC) and Show Racer (SR) pigeon aortic smooth muscle cells. The gene(s) responsible for atherosclerotic resistance in cultured SR smooth muscle cells (SMC) were hypothesized to be silent or down regulated in the WC. In the reciprocal experiments, it was hypothesized that the gene(s) …
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The central role of the neutrophil in ischaemic/reperfusion injury
… be affected by endothelial cell hypoxia the contractility of vascular smooth muscle was examined. Neutrophil adhesion to ECV304 cells, which had been hypoxic for 4 hours and then reoxygenated for 30 minutes, was significantly increased. This response was probably initiated by reactive oxygen …
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Generation and characterization of spred-2 knockout mice
… high and specific Spred-2 expression in vascular smooth muscle cells and previous studies showed an interaction of Spreds with RhoA, a key regulator of vascular smooth muscle contraction, the regulation of smooth muscle contractility seems to be a good candidate of this phenomenon. Moreover, …
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Integration of signalling in smooth muscle caveolae
… in this thesis examine the role of caveolae in smooth muscle function. Ca2+-sensitization is a contractile process depending on inhibition of myosin phosphatase activity. Here I test whether protein kinase C and Rho-associated kinase-mediated Ca2+ sensitization depends on caveolae using gene …