Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"small interfering ribonucleic acid (siRNA)"”.
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Engineering multimodal nanoparticles to combat triple-negative breast cancer
… utility in delivering chemotherapeutic agents or small interfering ribonucleic acid (siRNA) therapeutics to TNBC cells. ☐ The first aim of this thesis focused on developing NPs coated with anti-FZD7 antibodies and/or siRNA targeting β-catenin, a downstream protein in the Wnt pathway that is a key …
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Endocytosis mechanism of poly- and lipoplexes in siRNA delivery in HeLa cells
… of virtually any gene, and it is initiated by small interfering RNA (siRNA) molecule. siRNA is a 19 nucleotides-long double stranded RNA-molecule. In order to begin gene silencing, siRNA needs to be delivered to the cytosol. The first of the barriers that stand on the path of the siRNA delivery …