Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"small heat-shock protein (sHsp)"”.
-
Degradation of the E. coli small heat-shock proteins by the AAA+ protease lon : significance to protein quality-control
… and elimination of damaged and aggregated proteins requires the concerted effort of several branches of the protein quality-control network. This network includes refolding chaperones, disaggregases, holdases and proteases. Many years of investigation have led to a partial understanding of …
-
Characterization of a Beta-glucosidase Aggregating Factor Responsible for the Null Beta-glucosidase Phenotype in Maize (Zea mays L.)
… aggregating factor (BGAF). BGAF is a 32 kD protein that binds specifically to β-glucosidase and renders it insoluble during extraction. The data unequivocally demonstrate that BGAF is solely responsible for β-glucosidase aggregation and insolubility, and thus, the apparent null phenotype. …
-
The sHsp expression signature in the brain and modulation in models of chronic neurodegeneration
Intrinsic protein folding pathways are modulated by molecular chaperones, such as the diverse<br/>group of heat shock proteins (Hsps). Among these is the small heat shock protein (sHsp)<br/>family which in the mammalian genome consists of 10 low molecular weight (15-30kDa)<br/>members. The sHsps …
-
Contributions of aromatic pairs of human Gamma-D-Crystallin to its folding, stability, aggregation, and interaction with human Alpha B-Crystallin
Two distinct groups of proteins, a-crystallins and [Beta][gamma]-crystallins, constitute 90% of the vertebrate eye lens soluble proteins. Long-term solubility and stability against unfolding and aggregation are essential properties of crystallins and crucial to the function of the lens. Aggregation …