Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"small animal imaging"”.
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Frequency domain fluorescent molecular tomography and molecular probes for small animal imaging
… using a single source and detector pair for small animal imaging. In our system, the intensity of laser source is modulated to produce a diffuse photon density wave in the tissue. The phase of the diffuse photon density wave is measured by comparing the reference signal with the signal from …
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Development of novel emission tomography system
In recent years, small animals, such as mice and rats, have been widely used as subjects of study in biomedical research while molecular biology and imaging techniques open new opportunities to investigate disease model. With the help of medical imaging techniques, researchers can investigate …
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Measurement of retinal vascular permeability in a rat model using spectroscopic optical coherence tomography
… non-contact, noninvasive, cross-sectional imaging of the retina and anterior eye in real time, has dramatically improved in its resolution and speed in the recent years. In addition to the advancement in hardware, different OCT methods for functional measurements, such as Doppler OCT for …
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Sviluppo di un tomografo multi-energy per lo studio pre-clinico di nuove metodiche diagnostiche finalizzate al riconoscimento precoce della patologia tumorale
A new multi-energy CT for small animals is being developed at the Physics Department of the University of Bologna, Italy. The system makes use of a set of quasi-monochromatic X-ray beams, with energy tunable in a range from 26 KeV to 72 KeV. These beams are produced by Bragg diffraction on a Highly …
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Image Reconstruction of the Speed of Sound and Initial Pressure Distributions in Ultrasound Computed Tomography and Photoacoustic Computed Tomography
… computed tomography (PACT) are two emerging imaging modalities that have a wide range of potential applications from pre-clinical small animal imaging to cancer screening in human subjects. USCT is typically employed to measure acoustic contrasts, including the speed of sound (SOS) …
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Methods and adaptations required to perform small-animal MRI scanning using a large bore clinical MRI
Small-animal imaging has been widely implemented to study succession of disease, therapeutic treatments and the effects of environmental insults. The gold standard noninvasive technique for following progression of heart failure in small-animal models is magnetic resonance imaging (MRI). The aim of …
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Integración de imágenes biomédicas : técnicas basadas en teoría de la información
… multimodales (anatómicos y funcionales) de animales de laboratorio mediante técnicas basadas en teoría de la información. Se realiza un análisis de la influencia de los parámetros del algoritmo de registro, así como una validación sistemática de los resultados. Para poder evaluar el …
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Dynamic Contrast-Enhanced MR Microscopy: Functional Imaging in Preclinical Models of Cancer
… (DCE) MRI has been widely used as a quantitative imaging method for monitoring tumor response to therapy. The pharmacokinetic parameters derived from this technique have been used in more than 100 phase I trials and investigator led studies. The simultaneous challenges of increasing the temporal …
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Non-invasive in vivo ultrasound temperature estimation
… its safety and efficacy.The advent of diagnostic imaging tools for guidance of thermal therapy was a key factor in the clinical acceptance of these minimally invasive or noninvasive methods. More recently, ultrasound and magnetic resonance (MR) thermography techniques have been proposed for …
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Real-time membrane puncture detection using force sensors for micro-injections in phantoms
… target will squander research time, experimental animals and other resources. An ultrasound-guided robot developed at Robarts Research Institute was revised to implement closed-loop force feedback to compensate for tissue deformation during micro-interventions. Force sensors can detect puncture …
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Sistemas tomográficos multimodalidad para animales de laboratorio
… evaluación del rendimiento de tomógrafos PET de animales de laboratorio. Para caracterizar el sistema SPECT, al no existir un protocolo estándar para pequeño animal se ha seguido un protocolo similar al utilizado para sistemas de humanos y se han realizado estudios in vivo con roedores y con …
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Measurement of The Vascular Input Function In Mice For Dce-Mri
DCE-MRI is an important technique in the study of small animal cancer models because its sensitivity to vascular changes opens the possibility of quantitative assessment of early therapeutic response. However, extraction of physiologically descriptive parameters from DCE-MRI data relies upon …
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Development of a Three-Dimensional Image-Guided Needle Positioning System for Small Animal Interventions
Conventional needle positioning techniques for small animal microinjections are fraught with issues of repeatability and targeting accuracy. To improve the outcomes of these interventions a small animal needle positioning system guided by micro-computed tomography (micro-CT) imaging was developed. …