Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 42 for “"skin tissue"”.
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Opto-Physiological Modelling: On Light Interaction in Skin Tissue
… the mathematical underpinnings of how light and skin tissue interact. In this dissertation we present a mathematical framework and multi-stage methodology to model the interaction of light in skin tissue and recover underlying physiological information from images and videos of skin tissue. In …
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Investigation of variability in skin tissue intrinsic thermal conductivity measurements
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1995.
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Space radiation-induced bystander signaling in 2D and 3D skin tissue models
… different cell types cultured within 2D and 3D tissue architectures. 2D bystander signaling was investigated using a transwell insert system in which normal human fibroblasts (A) and keratinocytes (K) were irradiated with 1 GeV/n protons or iron ions at the NASA Space Radiation Laboratory using …
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The Design and Construction of a Bulge Testing Device Platform for Human Skin Tissue Applications
… data are available for anisotropic human skin tissue in biaxial loading configurations to suitably represent skin in vivo. Inconsistencies in mechanical and physical properties in the literature due to numerous physiological factors have restricted development of biaxial testing equipment …
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Skin Stories: Charting and Mapping the Skin. Research using analogies of human skin tissue in relation to my textile practice.
The practice based research SKIN STORIES:: CHARTING AND MAPPING THE SKIN deals with issues across the fields of art, design, technology, biology and material science. In an attempt to bridge the gap between aesthetics and technology by investigating the potential of new and industrial materials, …
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Multispectral Imaging of Skin Oxygenation
… technique for quantitative measurement of skin tissue oxygen saturation (StO2). Oxygen saturation is the percentage of oxygen carried in the blood over the total oxygen carrying capacity of blood. Skin StO2 is an important indicator of skin tissue clinical status. Measurement of skin tissue …
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Topical pharmacokinetics for a rational and effective topical drug development process
… data. It concludes that the knowledge of target skin tissue concentration would be key for a more rational drug development process. To this end, the primary objective of this thesis is to define a way of measuring drug concentration in skin tissue after topical application that is reliable, …
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Impact of Artificial UV Light Sources on the Skin
… per year) it was possible to use this data in a skin cancer mathematical model. The time-dose model is based on cumulative lifetime exposure dose and age. The first step was to apply plausible sunbed habit scenarios using the collated emission<br/>data which was used in a mathematical model to …
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The Electrical Properties of Human Tissue for the Diagnosis and Treatment of Melanoma Skin Cancer
… of a novel method for the diagnosis of melanoma skin cancer. First, a background about human skin tissue is presented. Then, a detailed description of melanoma along with current diagnosis techniques and treatment options are presented. In the experimental methods, the electrical properties of …
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1.2-micron multi-section quantum dot superluminescent diodes
… are of interest for use in medical imaging of skin tissue especially in the field of optical coherence tomography (OCT). In this thesis a ridge-waveguide multi-section quantum dot SLD that emits at 1.2μm with a bandwidth greater than 100nm and a power greater than 0.2mW is presented. The …
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The effects of ultraviolet-B radiation on antioxidant status and survival in the zebrafish.
… doses of UV-B radiation on muscle and skin tissue antioxidants in mature zebrafish (Brachydanio rerio) and on their hatching success and survival in early life stages was measured. Exposure of mature fish to sub-ambient doses of UV-B radiation both in the presence (1.28 W/m$\sp2$) and …
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Developing platforms to investigate mechanotransduction during wound healing
Wound healing in adult skin tissue lacks the ability to recapitulate uninjured tissue structure-function, forming instead fibrotic tissue with limited functionality. The extracellular matrix regulates forces on a cell- and tissue-specific level. Fibronectin, a mechanically regulated extracellular …
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Siam weed based hydrogel hybrid for tissue engineering
Tissue engineered skin grafts have been considered as an auxiliary for replacement of damaged skin due to burns and injury. In previous studies, gelatin hybrid with natural remedy were used in order to create 3D environment for the skin grafts. However, these gelatin hybrids were not sufficient to …
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Imaging through scattering
… demonstrated to resolve blood flow speed within skin tissue. This method is based on a computational photography technique and coherent illumination. This method can be applied in diagnosis and monitoring of burns, wounds, prostheses and cosmetics. A particularly important application of this …
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A three constituent mixture theory model of cutaneous and subcutaneous tissue in the context of neonatal pressure ulcer etiology and prevention
… been shown to increase fluid flow in human skin <em>in vivo.</em> Towards the design of prophylactic protocols and treatment modalities for PrU management there is a need for an analytical model to investigate the local fluid flow characteristics of skin tissue under time-varying loading. In …
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Development of a System Model for Non-Invasive Quantification of Bilirubin in Jaundice Patients
… the blood stream diffuses into the surrounding tissue leading to a yellowing of the skin. An optical system integrated with a signal processing system is used as a platform to noninvasively quantify bilirubin concentration through the measurement of diffuse skin reflectance. Initial studies have …
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Immunomodulatory biomaterials to promote early transplant integration and wound healing
… that are able to accelerate wound healing and tissue integration through the local recruitment and education of anti-inflammatory, pro-regenerative subsets of immune cells that work to enhance tissue regeneration and alloimmunity by dampening immune activation and cytokine production of factors …
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The development of biomedical instrumentation using backscattered laser light
… are obtained from different depths within the skin tissue. The results indicate that some depth discrimination is obtainable using instruments operating at different wavelengths, however it is difficult to demonstrate the effect in vivo. In a separate study it was shown that pressure applied to …
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Characterization of in vivo human skin in response to mechanical indentation using optical coherence tomography
The biomechanical response of skin can reflect not only health or localized pathology, but also systemic disease or an abnormal physiological condition of an individual. Both the intrinsic stiffness of the solid constituents and the time-evolved redistribution of fluid within skin tissue can …
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