Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"skin barrier function"”.
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Improving the skin barrier function in atopic dermatitis
… AD (synonym eczema) is a chronic inflammatory skin disease. It affects between 10 to 20% of children and 1 to 3% of adults worldwide. It is an important cause of morbidity and is estimated to cost £465 million per annum to the UK. AD is part of a family of Th-2 driven diseases and is often the …
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Intrinsic alterations of the skin barrier function promote the pathogenesis of atopic dermatitis in dogs
… dermatitis (cAD) is a chronic inflammatory skin disease affecting up to 10% of the canine population, it is the second most common allergic disease in dogs. Canine AD has many similarities to human AD and for this reason the dog has been suggested to be a good animal model to study AD in …
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The Barrier Properties of the Skin of Aquatic and Semi-Aquatic Vertebrates
Vertebrate skin is a heterogeneous organ that acts as a barrier to the external environment. A crucial structure for skin barrier function is the tight junction (TJ) complex that links skin epidermal cells. TJ proteins have been examined in mammalian skin but little is known about skin TJ proteins …
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The damaging potential of pesticide formulations on human skin
… of pesticide entry into the body. Impairment of skin barrier function may increase systemic exposure and toxicological risk. This project examines barrier function impairment of human skin in vitro due to commercial liquid formulations of the pesticides pirimphos methyl and pirimicarb. Water …
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Analysis of the Role of Bacillus oleronius Proteins in the Induction of Rosacea and Evaluation of Novel Therapeutics for the Treatment of Dermal and Ocular Rosacea
… flushing, papule and pustules, thickening of the skin and oedema. Rosacea is a debilitating condition that can impact on a patients emotional and psychological state. The aetiology of this dermatological condition is unknown and multiple factors contribute to the onset of rosacea and exacerbate …
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Development of Mechanical Optical Clearing Devices for Improved Light Delivery in Optical Diagnostics
… clearing agents in vivo, especially in the skin, where the projective barrier function of the stratum corneum must be removed. Mechanical optical clearing is a recently developed technology which utilizes mechanical loading to reversibly modify light transport through soft tissues, and much …
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Melanocyte proliferation in wounded skin in vitro: a histological and immunohistochemical analysis
Wounding of skin initiates a complex series of overlapping cellular events that culminates in the formation of a scar. The negative consequence of most cutaneous scars is the lack of adequate repigmentation of the neoepidermis. In order to effect successful wound healing by restoration of effective …