Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"skeletal muscle dysfunction"”.
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Effects of emphysema and chronic hypoxemia on skeletal muscle oxygen supply and demand
Skeletal muscle dysfunction in chronic obstructive pulmonary disease (COPD) is a condition in which peripheral skeletal muscle undergoes myopathic changes which impair muscle function, limit physical performance, and can lead to significant disability. While the etiology of the dysfunction is …
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THE EFFECT OF SDF1α ON SKELETAL MUSCLE REGENERATION AFTER COMPARTMENT SYNDROME INJURY
Introduction: Skeletal muscle dysfunction, whether due to injury, disease or age, can be debilitating to normal life. There are few effective treatments for severe skeletal muscle injuries. SDF1α is a chemokine which promotes migration of stem cells through binding to the CXCR4 receptor and has …
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The independent and combined effects of rapamycin and metformin on naturally occurring osteoarthritis
… meniscal calcification, synovitis, and skeletal muscle dysfunction. Inhibiting the mechanistic target of rapamycin (mTOR) and stimulating AMP-activated protein kinase (AMPK) has extended lifespan and protected against post-traumatic (secondary) OA in mice. However, it remains unknown if …
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Increased Inflammatory Gene Expression in Masseter Muscle of an Orthognathic Surgery Subject with Obstructive Sleep Apnea
… diabetes, and in some cases, retrognathia and muscle dysfunction. The latter two conditions may prompt orthognathic correction. Past investigations have shown a genetic association with OSA. Given that masseter muscle influences skeletal malocclusion and is active during OSA, we investigated …
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Nampt-Mediated Nad+ Homeostasis in Skeletal Muscle: Implications for Healthy Aging
Mammalian skeletal muscle is a highly dynamic organ capable of structural and metabolic remodeling in response to exercise demands, nutrient supply, and environmental insults. Muscle also plays a central role in the maintenance of whole-body energy balance, capable of both storing and oxidizing …