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Showing 1 to 8 of 8 for “"sister chromatid exchange"”.

  1. DNA repair and sister chromatid exchange

    Hagelstrom, R. Tanner, author, Bailey, Susan M., advisor, Liber, Howard, advisorColorado State University. Libraries2008

    Mitotic recombination that occurs between sister chromatids, known as sister chromatid exchange (SCE), is a common event in mammalian cells; yet very little is understood about SCE. Likewise, the biological relevance of SCE to humans is also unclear. It is generally thought that SCE represents no …

    colostate Repository record

  2. Sister Chromatid Exchange In Chromosomes Of Untreated And Drug Treated Human Fibroblasts.

    Watson, Michael Shaw

    uab Repository record

  3. Cell Growth Paramenters and Sister Chromatid Exchange Level in Fibroblasts from a Patient Diagnosed with Bloom Syndrome

    James, Martha G.Drake University1985

    … growth factor, the mitotic index, and the sister chromatid exchange level of the KB fibroblasts with normal and known Bloom Syndrome control fibroblasts. Procedure. The growth responses of the KB, normal, and Bloom Syndrome cell lines to fibroblast qrowth factor were determined by culturing …

    drake Repository record

  4. The Immune Status of Two Bloom's Syndrome Siblings

    Bray, Janice J.Drake University1985

    … (BS). Due to lack of demonstrable increased sister chromatid exchange (SCE) in their blood cells and fibroblasts, diagnosis of BS is in question. Procedure. This study examined the immune reactions of these siblings with such tests of immune function as: T- and B-cells, T-cell subsets, …

    drake Repository record

  5. In vitro chemically-induced DNA damage in cancer patients and healthy individuals. The effect of genotoxic compounds in cells from polyposis coli, colon cancer patients and healthy individuals.

    Kurzawa-Zegota, MalgorzataUniversity of Bradford2011

    … assay, the Micronucleus ¿ FISH assay and the sister chromatid exchange assay. The food mutagens, PhIP and IQ, as well as titanium dioxide nanoparticles (TiO2 NPs) induced a dose dependent increase in the DNA damage and chromosomal abnormalities in all tested groups regardless of confounding …

    bradford Repository record

  6. Computational Discovery and Analysis of rDNA Sequence Heterogeneity in Yeast

    West, Claire LouiseUniversity of East Anglia2013

    … concerted evolutionary processes such as unequal sister chromatid exchange (USCE) and gene conversion (GC). In this study Perl software has been used to uncover rDNA sequence variation in the yeast Saccharomyces paradoxus, using data derived from the Saccharomyces Genome Resequencing Project. This …

    east-anglia Repository record

  7. Fancm and Faap24 Maintain Genomic Stability Through Cooperative and Unique Functions

    Wang, Yucai2013

    … They also cooperatively function to suppress sister chromatid exchange and radial chromosome formation, likely by limiting crossovers in recombination repair. In addition, I defined novel non-overlapping functions of FANCM and FAAP24 in response to ICL damage. FAAP24 plays a major role in …

    uthsc Repository record

  8. Role of ORCA/LRWD1 in the maintenance of telomere integrity

    Hsu, Rosaline Yuan-ChiehUniversity of Illinois at Urbana-Champaign2020

    … (APB) formation, c-circle level, and telomere sister chromatid exchange (T-SCE). The loss of ORCA induced overall increase in HR, suggesting that ORCA functions as a negative regulator for HR. The function of ORCA at ALT-telomeres is ORC-independent. ORCA directly binds to RPA and modulates the …

    uiuc Repository record