Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"singlet oxygen (1O2)"”.
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Triplet Excitons in Natural Photosynthetic and Artificial Light Harvesting Systems: Measurement and Modeling.
… the result of the generation of highly reactive singlet oxygen (1O2) by energy transfer from the (B)Chl triplet state (3(B)Chl) to the oxygen ground state. Natural photosynthetic systems must protect themselves from 1O2, typically done by positioning carotenoids within a few angstroms of each …
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Roles of singlet oxygen and triplet excited state of dissolved organic matter formed by different organic matters in bacteriophage MS2 inactivation
Inactivation of bacteriophage MS2 by reactive oxygen species (ROS) produced by irradiation with simulated sunlight, containing visible light and ultraviolet light with wavelengths greater than 320 nm, was investigated. The results from experiments with synthetic sensitizers Rose Bengal, …
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Photoresponsive nanosystems for therapeutic applications
… generation of cytotoxic species, such as singlet oxygen (1O2) and nitric oxide (NO), by using appropriate photochemical precursors represents a fascinating and unconventional approach for the treatment of cancerous and microbial diseases in non-invasive manner. However, many precursors …
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Photochemically produced reactive species generation by extracellular organic matter sensitizers from Chlamydomonas reinhardtii
… the generation of reactive species, including singlet oxygen (1O2), hydroxyl radicals (•OH), and triplet excited dissolved organic matter (3DOM). These reactive species can play an essential role in the mineralization of dissolved organic matter, nutrient cycling and bioavailability, …
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The synthesis of aza-dipyrromethenes as potential pdt agents and measurement of singlet oxygen generation.
… using a photosensistiser that produces cytotoxic singlet oxygen (1O2) after light irradiation. Current approved photosensitisers have limitations, such as a low extinction coefficient in the desired therapeutic wavelength of absorption (600 “ 900 nm), as in the case of Photofrin®. The discovery …
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Singlet oxygen generating luminescent lanthanide complexes with naphthalimide-based and oligothiophene-based sensitizers
… lanthanide (LnIII) complexes that also generate singlet oxygen (1O2) are of interest to medical, biological, and analytical fields, as they can provide cytotoxicity and luminescence using light excitation. Because of the interest in these compounds, systematic studies were used to help understand …
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Consequences of Oxidative DNA Damage: Base-Pair Dissociation, Singlet Oxygenation and DNA-Protein Crosslinking
… being more vlunerable to ionizing radiation and singlet oxygen (1O2) damage. Leveraging on our previous accomplishments on the study of gas-phase reactions of 1O2 with 2′-deoxyguanosine radical cations, my research thesis expanded to the investigation of reaction dynamics of 9-methyl-8-oxoguanine …
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SVILUPPO E PROGETTAZIONE DI SISTEMI FOTOATTIVABILI PER TERAPIE OFTALMICHE
… generating nitric oxide (NO) and/or singlet oxygen (1O2) under visible light stimuli. If produced with accurate spatio-temporal control, these species, can act as “unconventional” therapeutics against infections, glaucoma and macular degeneration. In addition, they also offer two …
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Covalent Post-Assembly Modification of Metal-Organic Capsules
… incorporate between one and five equivalents of singlet oxygen (1O2), whereas cobalt(II) capsules react fully and incorporate six equivalents of 1O2 . Structural changes following these reactions impacted the host-guest chemistry of the cobalt(II) cages, and binding studies using isothermal …
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Pharmacophore-directed retrosynthesis (PDR) and Density functional theory studies applied to the potent ion channel inhibitor waixenicin A : synthetic studies toward a more stable salarin C congener, thia-salarin C, through the lens of PDR.
… SalC also exhibits extreme instability towards singlet oxygen (1O2) through a Wasserman rearrangement, even concentrations present in ambient air, causing difficulties in both synthetic endeavors and manipulations during previous biological studies. This led us to hypothesize that replacing the …
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Photochemical processes in engineered aquatic systems for remediation of per- and polyfluoroalkyl substances and algae cultivation
… matter (3DOM*), hydroxyl radicals (HO•), and singlet oxygen (1O2). Comparisons with Suwannee River natural organic matter (SRNOM) showed that EOM solutions exhibited lower light absorption and reactive species production than SRNOM solutions per mg-C·L−1. However, 3DOM* quantum yield …
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Fluorinated Metallo Phthalocyanines for Chemical and Biological Catalysis
<p>The rational design of robust oxidation catalysts based on organic molecules is hindered by the presence of labile C-H bonds. We have shown recently that replacing all C-H bonds by a combination of fluoro- and perfluoro-groups in a bioinspired Cytochrome P450 model based on a phthalocyanine, Pc, …
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EMISSIVE PEPTIDE NUCLEIC ACIDS (PNAS): POTENTIAL TOOLS FOR INNOVATIVE DIAGNOSTICS AND THERAPEUTICS
… as photosensitizers (PSs) generating cytotoxic singlet oxygen (1O2) for applications in photodynamic therapy (PDT)7. Moreover, they show good cell permeability, for example towards cancer cells. In this research activity, in collaboration with Professor Maggioni (University of Milan), the …