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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 5 of 5 for “"single-ion channel"”.

  1. Silicon nanopore patch clamp device for measuring single ion channel activity

    Plucinski, LisaUniversity of Illinois at Urbana-Champaign2015

    … neural activity is of high interest with applications in neuron and neural circuit functioning as well as high-throughput ion channel screening for early drug development research. In 1991 Erwin Neher and Bert Sakmann received the Nobel Prize for their invention of the patch clamp, which is based …

    uiuc Repository record

  2. The mechanism of HAMLET-induced cell death - cellular signalling, oncogenes and clinical perspectives

    Storm, PetterInst för laboratoriemedicin, Lund2012

    … the ‘’Hallmarks of cancer’’. Using a combination of shRNA screens, proteomic and metabolomic technology, we identified the c-Myc oncogene and hexokinase as essential determinants of HAMLET sensitivity. HAMLET sensitivity was modified by the glycolytic state of tumor cells and HAMLET induced a …

    lund Repository record

  3. Computer Simulation of Biological Ion Channels

    Hoyles, Matthew1999

    … are developed for the rapid and accurate solution of Poisson's equation in the presence of a dielectric boundary and multiple point charges. These algorithms are then used to perform Brownian dynamics simulations on realistic models of biological ion channels. An iterative method of solution, …

    aus-cath Repository record

  4. Computer Simulation of Biological Ion Channels

    Hoyles, Matthew1999

    … are developed for the rapid and accurate solution of Poisson's equation in the presence of a dielectric boundary and multiple point charges. These algorithms are then used to perform Brownian dynamics simulations on realistic models of biological ion channels. An iterative method of solution, …

    anu Repository record

  5. Synthetic Ion Channels From Lipophilic Guanosine Derivatives

    Ma, Ling2009

    Synthetic ion channels and pores not only represent models of natural transmembrane ion channels, but also demonstrate their potential applications in the areas of drug delivery, biosensors, antimicrobial agents and other molecular devices. In this thesis, lipophilic guanosine derivatives that …

    maryland Repository record