Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"single-cell characterization"”.
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Biophysical approaches to single-cell characterization
High-throughput single-cell RNA-seq (scRNA-seq) is used to describe complex tissues by characterizing transcriptional states of individual cells. Defining a cell’s position, both in regard to tissue margins and its social context, is essential for understanding the intrinsic and extrinsic variables …
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Combining optical and hydrodynamic forces for single cell characterization, isolation and delivery
With the existence and emerging importance of cellular heterogeneity there has been a push in the microbiology community for new tools to study at the individual cells. To meet the need to identify, characterize and isolate single cells of interest from bulk samples, precise and directed forces on …
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Leveraging Single Cell Technologies For The Characterization and Treatment of Refractory Pancreatic Cancer
… hallmark of cancer, and the advent of multimodal single-cell technologies has helped uncover heterogeneity in a high-throughput manner in different cancers across varied contexts at an unprecedented resolution. In an effort to improve precision medicine approaches in pancreatic ductal …
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Single Cell Analysis of the HIV-1 Latent Reservoir
… of rare, long-lived, latently infected cells. These cells, called the latent reservoir, are thought to resist immune clearance and viral cytopathic effects by harboring a transcriptionally quiescent integrated HIV-1 provirus. As a result, interruption of suppressive therapy almost …
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Instrument development for the analysis of low abundance analytes in single cells and small volume samples
Understanding the cell-to-cell differences between cells is important for both fundamental biology and in identifying normal and pathological functioning. Biogenic amines, which include catecholamines and indolamines, are of particular interest due to their presence throughout the central and …
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Eomes Directs the Formation of Spatially and Functionally Diverse Extra-Embryonic Mesoderm Derived Tissues
… embryonic development, the first mesodermal cells to originate at the posterior primitive streak will give rise to the extra-embryonic mesoderm (ExEM). These cells will contribute to key tissues supporting the development of the embryo, including the amnion, chorion, yolk-sac, and allantois. …