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Showing 1 to 1 of 1 for “"single chain MHC trimer"”.
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Single chain MHC trimer-based DNA vaccines for pathogen protection
… limitations, we have developed fully assembled MHC molecules that can be expressed as membrane-bound proteins on the cell surface, termed single chain trimers: SCTs). SCTs are composed of an immunodominant peptide, β2m, and MHC I heavy chain covalently linked by 15-20 amino acid flexible …