Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"single cell proteomics"”.
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Development of tools for single molecule peptide fluorosequencing
… As each molecule is individually monitored, this single molecule method is useful for the discovery of low abundance peptides and single cell proteomics. New tools are needed to improve sequencing and label new amino acid residues in selective fashion with fluorophores. Single molecule peptide …
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Proteome-Seq: Sequencing-Based Readout Of Proteomic Analytical Assay
Cell functional states undergo rapid changes during development and in disease states, reflecting heterogeneity inherent to cellular systems. This heterogeneity arises from multiple factors, including environmental cues, genomic variations, epigenetic modifications, transcriptional dynamics and the …
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Metabolic heterogeneity in microbial populations
No two living cells are exactly the same. Even cells from a clonal population with identical genomes living in the same environment will express proteins in different numbers simply due to the random nature of the chemistry involved in gene expression. The consequences of this stochastic gene …
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Cell Fate Decisions in the Early Mammalian Embryo
… from the totipotent zygote via two successive cell fate decisions in the appropriate sequence, position and proportion, to generate a blastocyst capable of implantation and further development. In mammals this process has long been thought to be regulative, with cell-cell interactions flexibly …
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Advances in biophysical characterisation through micron scale flow engineering
Proteins are the chief actor molecules of cells central to the majority of biochemical and biophysical processes that sustain life. Interactions between proteins and other biomolecules are crucial to a faultless execution of biological function, yet it has remained challenging to analyse these …