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Showing 1 to 1 of 1 for “"simplified paclitaxel"”.
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Design, Syntheses and Biological Activities of Paclitaxel Analogs
The conformation of paclitaxel in the bound state on the protein has been proposed to be the T-taxol conformation, and paclitaxel analogs constrained to the T-taxol conformation proved to be significantly more active than paclitaxel in both cytotoxicity and tubulin polymerization assays, thus …