Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"signalling centre"”.
-
The evolution and function of pharyngeal arch signalling centres in jawed vertebrates
… chapter, I demonstrate a requirement for Fgf signalling in endoderm–ectoderm fusion and gill slit formation in a cartilaginous fish, the little skate (Leucoraja erinacea). Once formed, skate gill arches expand laterally, and give rise to cartilaginous appendages called branchial rays, which …
-
Studies of the hindbrain roof plate organiser in the chick embryo
… the gdf7- positive roof plate boundary and its signalling properties can be regenerated in roof platederived tissue at the interface between hindbrain roof plate epithelium and neuroepithelium. Further, this gdf7-positive boundary is required for the expression of cath1, which marks the …
-
Axial patterning of the chondrichthyan pharyngeal endoskeleton and the origin of the jaw
… develops under the influence of a shh-expressing signalling centre, in a manner that parallels that shh-dependent development of branchial rays (i.e. cartilaginous appendages that support the respiratory lamellae of the gill arches). Taken together, this dissertation presents evidence for serial …
-
Cellular principles of Xenopus appendage regeneration
… Identification of ROCs suggests that signalling centres and stem/progenitor cells in their proximity are critical requirements to build a lost appendage. Next, I found that the immune system of regeneration-competent tadpoles use reparative myeloid lineage cells that have an impact on …
-
Spatial Transcriptome Profiling of Gastrulating Primate Embryos
… In my PhD project, I aimed to delineate the signalling environment of spatially defined tissues of early gastrulating embryos, using the marmoset, an established primate model, to study conserved human postimplantation embryo developmental processes. I first characterised marmoset embryos of …