Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"signaling endosome"”.
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Interplay of Brain Derived Neurotrophic Factor and Protein Kinase A in Modulating Mitochondrial Structure and Function in Brain Homeostasis and Disease
… rapid endocytosis and translocation of the signaling endosome to the mitochondria leading to elevated activation of Protein Kinase A (PKA). BDNF-mediated activation of mitochondrial PKA led to an increase in phosphorylation of fission modulator Drp1, and of mitochondrial adaptor protein …
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THE EFFECT OF SKELETAL MUSCLE-SYNTHESIZED BDNF ON MOTOR NEURON SOMA SIZE AND BDNF PROTEIN ABUNDANCE
… endocytosis of the complex and an intracellular signaling cascade that recruits dynein motor proteins for retrograde transport of the BDNF/TrkB endosome to the motor neuron soma. At the motor neuron soma, the BDNF/TrkB complex activates cyclic Adenosine Monophosphate (cAMP) response element …