Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"sib-pair"”.
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A linkage study of autism using multipoint sib-pair analysis
… that the recurrence risk for autism among siblings of autistic children is 50-200 times higher compared to the risk of autism in the general population (4-5 in I 0 000 births). Thirdly, twin studies show a significantly higher concordance rate among monozygotic twins compared to dizygotic …
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Clinical and genetical aspects of Celiac Disease
… study has been to estimate the risk of a third sibling being aff ected in CD sib-pair families, identify the chromosomal region containing susceptibility genes in CD and study the genotype-phenotype association in CD. Material was collected from 107 families with at least two aff ected siblings, …
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Methods Development in Inflammatory Bowel Disease
… learning approaches in a discordant/concordant sib-pair study. The machine learning methods used were iClusterPlus and MoCluster. The iClusterPlus analysis yielded four “top priority” genes with GBP2 as a novel discovery in IBD. MoCluster yielded 10 “top priority” genes with CSK as a novel …
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Adipose tissue-derived serum amyloid A and adipose tissue macrophages in metabolic disease
… adipose tissue have both been suggested as possible players behind obesity-related comorbidities in humans. The aim of this thesis was to investigate if there are obesity-independent links between adipose tissue macrophages and metabolic dysfunction and to examine if adipose tissue-derived SAA …
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Genetica molecolare dell'autismo: studi di associazione ed analisi di geni candidati
… a neurodevelpmental disorder characterized by impaired verbal communication, limited reciprocal social interaction, restricted interests and repetitive behaviours. Twin and family studies indicate a large genetic contribution to ASDs (Autism Spectrum Disorders). During my Ph.D. I have been …