Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"siRNA therapy"”.
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Novel Lipid Polymer Design for Nucleic Acids Delivery
… the approval of the first small interfering RNA (siRNA) therapy and the rapid deployment of LNP-based mRNA vaccines against COVID-19. However, achieving efficient and targeted delivery of nucleic acids to solid tumors remains a significant barrier. Polyethyleneimine (PEI), in particular, was once …
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RNA Therapeutics for Fibrolamellar Hepatocellular Carcinoma
… efficacy of conventional treatments such as chemotherapy and radiation my work explored new therapeutic options. As DNAJB1::PRKACA is known to initiate tumorigenesis, I reasoned that it would be an ideal target for a therapeutic. However, it was not known if FLC tumors are still dependent on …