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Showing 1 to 2 of 2 for “"short open reading frames"”.

  1. Functions of the eukaryote-specific ribosomal protein Asc1 /RACK1 in gene-specific translational activity

    … translation of a specific set of mRNAs with short open reading frames (ORFs), including those that encode ribosomal proteins and nuclear-encoded mitochondrial components. Consistent with these translation defects, ASC1 mutants are unable to grow in conditions requiring full mitochondrial …

    mit Repository record for Functions of the eukaryote-specific ribosomal protein Asc1 /RACK1 in gene-specific translational activity (opens in a new tab)

  2. Gene misexpression in humans

    … disorders, had fewer enhancers and were shorter compared to non-misexpressed genes. Using 2,821 paired whole genome and RNA sequencing samples from the INTERVAL study, I observed that misexpression events were enriched for nearby rare structural variants (SVs) but not rare single …

    cambridge Repository record for Gene misexpression in humans (opens in a new tab)