Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 104 for “"shape-change"”.
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Molecular Determinant of Mitochondrial Shape Change
Mitochondria shape cytosolic Ca2+ (cCa2+) transients. Ca2+ entry into the mitochondria is driven by the highly negative mitochondrial membrane potential and through a highly selective channel, the Mitochondrial Calcium Uniporter (MCU). Mitochondrial Ca2+ (mCa2+) is utilized by the matrix …
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Paths Towards Shape Change: Elastic Instabilities and Spontaneous Deformations
A system can change shape. In biology, shape changes lead to the wonderful variety of forms that surround us; in engineering, they are a tool to design soft robots and deployable structures. In this thesis, we identify and explore three fundamental paths that lead to shape change: elastic …
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Structural correlates of shape change in the primate crystalline lens
Cytological changes associated with accommodation in macaques and man were investigated using light and scanning electron microscopy to examine lenticular fibre modification and the role of the lens capsule. Accommodation was simulated monocularly in one animal with local administration of 1/4% …
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Shape change for global vorticity shedding and added mass energy recovery
… of octopodes enabled by their dynamic mantle shape change. For the octopus, the dynamic shape change, from an initially hyper-inflated nearly spherical shape to a streamlined ellipsoidal shape, allows for substantial added mass energy recovery from the fluid during fast jet escapes, that …
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Experimental and Theoretical Investigations of Electrode Shape Change Taking Place During Pitting Corrosion of Iron
… experimental measurements of corrosion pit shapes and theoretical calculations on the effect of pit shape on the mass transport of dissolved metal ions within pits. The system studied was pure iron in 1N H(,2)SO(,4) containing small amounts of chloride ion.
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Reimagining the Inner Ear: A Morphometric Modeling Approach for Establishing Shape Change in the Evolution of the Human Otolith System
… spherical harmonic-based and landmark-based shape analyses. The model establishes the relationship between the external bony and internal membranous tissues of the otolith system which enables the reconstruction of soft tissue from bone. This approach is a powerful tool to assess functional …
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Morpho : a self-deformable modular robot inspired by cellular structure
… contract and expand to control individual cell shape, and sheets of such cells undergo large-scale shape change through the cooperative action of connected cells. Such deformations play a role in many processes: early embryo shape change, heart and intestine function, and in lamprey locomotion. …
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Sketching as a support mechanism for the design and development of shape-changing interfaces
Shape-changing interfaces are a novel computational technology which incorporate physical, tangible, and dynamic surfaces to create a true 3-Dimensional experience. As is often the case with other novel hardware, the current research focus is on iterative hardware design, with devices taking many …
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The influence of oxidised low density lipoproteins on platelet activation
… ADP dependent. However, oxLDL was able to induce shape change, one of the earliest stages of platelet activation, independently of secondary agonists. Platelet shape change requires the protein myosin, the activity of which is controlled by the phosphorylation of its regulatory light chains (MLC) …
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Centrosome-organized plasma membrane infoldings linked to growth of a cortical actin domain
Regulated cell shape change requires the induction of cortical cytoskeletal domains. Actin is a cytoskeleton protein that makes up the cortex and drives cell shape change. Signals to induce actin polymerization can come from external or internal cues. Often, local changes to plasma membrane (PM) …
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Regulation of blood platelet function by nitric oxide
… adhesion, activation, aggregation, secretion and shape change. In this study the effects of NO on Ca²+ dependent and independent pathways of activation were investigated. The data produced during the course of this study reveals new insights into the mechanisms by which NO regulates platelet …
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Kinematic Synthesis of Planar, Shape-Changing Rigid Body Mechanisms for Design Profiles with Significant Differences in Arc Length
Design of shape-changing machinery is an area of growing significance. Shape-change may be employed in the near future to vary the cross section of a wing, create flow-field control by altering shapes to locally affect downstream fluid behavior, or vary the size of a car seat to meet a wider array …
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1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine (Platelet Activating Factor): Interactions with Sheep Platelets
… and more satisfactory method based on platelet shape change. The development of the latter was based on microscopic and rheooptic observations but is also supported by theoretical considerations. A shape change parameter (SCP) was defined and, therefore, the method is called the SCP assay. The …
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Parameterized Shape Adaptive Material: A New Design Method for Inclusive Sportswear
… design does not take into account body size changes that many individuals experience (i.e. through pregnancy, menstruation, etc.). This study focuses on transforming multi-stable mechanisms into composite form to create shape adaptive wearable materials for periods of body size and shape …
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Ontogeny and evolutionary morphology of the skeleton in frogs
… context. Second, studies are made of ontogenetic shape change in the skull using thin-plate spline morphometrics. Important differences between pipoid skull development and that of other frogs are uncovered. These include the convergent evolution of primitive ossification patterns still retained …
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TGF-β1-induced Chloride Channel Activity and Migration of Human Eosinophils
… chamber. Flow cytometry was used to determine shape change.|The results showed that TGF-β1 stimulation increased protein expression of ClC-3. There was also more CLC-3 protein expression in asthmatic eosinophils than normal eosinophils. TGF-β1 increased protein expression of PKC-β1, PKC-δ, and …
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Quantifying, Understanding and Predicting Differences Between Planned and Delivered Dose to Organs at Risk in Head & Neck Cancer Patients Undergoing Radical Radiotherapy to Promote Intelligently Targeted Adaptive Radiotherapy
… and avoid organs at risk (OARs), but anatomical change during treatment mean that the radiation dose delivered to the patient – delivered dose (DA), is different to that anticipated at planning – planned dose (DP). Modifying the RT plan during treatment – Adaptive Radiotherapy (ART) – could …
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Investigation of the Lanthanide Sesquioxides as High Temperature Transformation Toughening Agents
… involves an 8-10% volume expansion and a shape change ($\Delta\beta$) of $\sim$10$\sp\circ$. Techniques used in the investigation of the transformation behavior included: grinding, cooling in liquid nitrogen, DTA, dilatometry, ambient and high temperature Vickers indentation, and …
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An Experimental Investigation on the Performance of a Shape Changing, Bio-inspired F2MC Panel
… undergoing oscillatory heave motions and active shape change. The shape change will be achieved using a panel embedded with Fluidic Flexible Matrix Composite (F2MC) tubes for actuation. A beam, or plate strip, model is presented as a means of verifying that F2MC tubes can effectively serve as a …
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Attitude control via structural vibration : an application of compliant robotics
… controlled by the imposition of a bounded cyclic shape change-the canonical example of such a system is a cat righting herself while falling, thereby always landing on her feet-coupled with the conservation of angular momentum, which acts analogously to a nonholonomic constraint on the system …
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