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Showing 1 to 2 of 2 for “"sfRNA"”.

  1. The Modulation of Innate Immunity by Cellular and Viral Noncoding RNAs

    … which produces subgenomic flaviviral RNA (sfRNA), capable of inhibiting the innate immune system. We identified DENV-2 sfRNA in mosquito saliva using three different methods: northern blot, RT-qPCR and RNA sequencing. Salivary sfRNA is protected in detergent-sensitive compartments, which we …

    utmb Repository record for The Modulation of Innate Immunity by Cellular and Viral Noncoding RNAs (opens in a new tab)

  2. Investigating the importance of the Zika virus 3′ untranslated region to viral fitness

    … in RNA structure in the Site B mutant, and thus sfRNA production. Additionally, sfRNA production was found to be restored following the single nucleotide reversion. Further investigations linked the hampered sfRNA production to reduced virion production in IFN competent A549 cells, which was not …

    cambridge Repository record for Investigating the importance of the Zika virus 3′ untranslated region to viral fitness (opens in a new tab)