Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 31 for “"sex steroids"”.
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The Influence of Ovarian Sex Steroids on Insulin Receptor Status in Mice
… and low plasma concentrations of the ovarian sex steroids respectively. Unchanged insulin binding data suggested that this increase in insulin action was mediated at the post-receptor level in both skeletal muscle and liver. Neither 2 weeks ovariectomy nor the 2 week oral administration of …
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The role of sex steroids in the regulation of the Obese gene and leptin secretion
Leptin, the hormone product of the Obese (Ob) gene, is secreted from adipocytes to communicate energy status, reduce food consumption and increase metabolism of fat stores. Interestingly, females have higher leptin levels than males in humans, rodents, and other mammals, even when adjusted for fat …
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Studies on the Role of Natural and Synthetic Sex Steroids in the Regulation of Carbohydrate Metabolism
… examines the effects of natural and synthetic sex steroids on the regulation of glucose homeostasis in adult female mice. Natural (estradiol-17B) and synthetic (ethynyl estradiol) estrogens elevate plasma insulin concentrations, glycogen deposition and peripheral glucose utilisation, and reduce …
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Influence of Insulin, Insulin-Like Growth Factor I and Sex Steroids On the Regulation of the Vitellogenin Receptor In Developing Oocytes of Largemouth Bass (Micropterus Salmoides)
<p> Fish vitellogenin synthesized and released from the liver of oviparous animals is taken up into oocytes by the vitellogenin receptor (<italic>vtgr</italic>). This is an essential process in providing nutrient yolk to developing embryos to ensure successful reproduction. Here we disclose the LMB …
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Hormones and behaviour during the menstrual cycle
… this thesis aimed to investigate emotional and sexual variations experienced by women during the Menstrual Cycle including the phenomenon of "Premenstrual Tension ", and relate such changes to the sex steroids, Oestradiol, Progesterone and Androgens.
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Hormoninės kontracepcijos poveikis moterų kognityvinėms funkcijoms ir emocinės informacijos apdorojimui /
… substantially suppressing endogenous levels of sex steroids through the inhibition of the hypothalamic-pituitary-ovarian axis and by adding effects of synthetic steroids. Previous research show that sex steroids are closely linked to women’s emotional well-being and cognitive functioning. …
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The effects of stress hormones on preferences for acoustic signals in female green treefrogs (Hyla cinerea) and barking treefrogs (Hyla gratiosa)
… rate independently of changes in circulating sex steroids. Results thus suggest that CORT production, which is known to be modulated by various intrinsic and extrinsic factors, can decrease the variance in male mating success and, thus, the strength of directional selection on call rate in …
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Psycho-endocrinological aspects in aging males and transsexual persons
Studies on the relationship between behaviour and sex steroids do not always provide consistent results. The aim of this thesis is to contribute to the clarification of certain endocrinological and psychoendocrinological aspects in two different clinical contexts. More subtle changes in androgen …
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Genetic and Sex Steroid Hormone Contributions to the Sexual Dimorphism in Murine Experimental Allergic Encephalomyelitis
… with susceptibility to EAE. Further, the role of sex steroid hormones and parent-of-origin effects were studied through the use of reciprocal crosses of SJL/J and BI0.S/SgMcdJ mice. We found that adult gonadal hormones selectively regulate sexually dimorphic quantitative traits observed in EAE at …
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Dehydroepiandrosterone and dehydroepiandrosterone sulphotransferase activity and expression in human disease
… effects via its downstream conversion to active sex steroids in peripheral target tissues. In contrast the conversion of DHEAS to androgens first requires cleavage of the sulfate group, catalysed by the microsomal enzyme steroid sulfatase (STS). Conversely, DHEA is converted to inactive DHEAS by …
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Age, growth, and reproductive biology, of the winter skate, Leucoraja ocellata, in the western Gulf of Maine
… the winter skate, plasma concentrations of the sex steroids testosterone (T), 17beta-estradiol (E2), and progesterone (P4) were determined by radio immunoassay and compared to morphological and histological changes occurring in the reproductive tract over a complete reproductive cycle for mature …
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Sex- and Training-Related Differences in Metabolic, Sex Steroid and Growth Hormone Responses During Prolonged Exercise
… (3) male runners, and (4) female runners. Sex- and training-related differences in resting levels and responses were described for glucose (GLU), lactic acid (HLa), hematocrit (Hct), respiratory exchange ratio (R), growth hormone (hGH), estradiol-B17 (E(,2)), and testosterone (T). Blood …
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Hormonal modulation of sex steroid hormone receptors and oncogenes in human breast cancer cells
Since sex steroids modulate breast tumor growth, and high levels of the HER-2/neu protooncogene protein may contribute to breast cancer metastasis, the effects of estrogen, progestin and hormone antagonists on the levels of estrogen receptor (ER), progesterone receptor (PR) and HER-2/neu mRNA and …
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Tracing Androgen Metabolism With Inhibition Of Aromatase In Breast Cancer: In Vitro Studies And Clinical Correlates
… platforms for reliable quantification of sex steroids at trace levels present in circulation in post-menopausal women and in women on AI. In this dissertation, rapid and highly sensitive LC-HRMS assays were applied in vitro to conduct a comprehensive analysis of biochemical efficacy of …
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Assessment of Anthropometric Development of Transgender and Gender Non Binary Youth Assigned Female at Birth Across Prepubertal and Pubertal Growth
… height are impacted by many factors including sex steroids. Increasing numbers of transgender and gender non binary youth who are assigned female at birth (transmasculine (TM) youth) avoid puberty with endogenous hormones by utilizing gender affirming hormone therapies (GAHT) including GnRH …
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Innleiðing einnar mæliaðferðar á LC-MS/MS fyrir átján sterahormón
… glucocorticoids, mineralocorticoids and finally sex steroids (adrenal androgens and estrogens). Steroid hormones regulate both physiological and developmental processes and they all have specific roles in metabolism and other bodily functions. Any deficiency, excess or buildup of intermediate …
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The Environmental Control of Reproduction in the Female Dace, Leuciscus leuciscus
… mid-March. During the annual ovarian cycle, the sex steroids E2 and T showed two clear elevations. The first occurred initially in April followed by a rise in serum calcium levels. This subsequently initiated the appearance of yolk granules in the oocytes in June. The second rise occurred in …
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