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Showing 1 to 20 of 40 for “"sex hormone"”.

  1. Computational ligand discovery for the human and zebrafish sex hormone binding globulin

    … ligands for the human and zebrafish sex hormone binding globulin (SHBG). The ‘benchmark set of steroids’ is a set of steroids with known affinities for human SHBG that has been widely used for validation in the development of different virtual screening methods. We have updated this …

    ubc Repository record for Computational ligand discovery for the human and zebrafish sex hormone binding globulin (opens in a new tab)

  2. Resting Microvascular and Autonomic Function in Relation to Age and Sex Hormone Concentrations

    This study assessed the influence of estradiol, progesterone, testosterone and age on resting microvascular and autonomic function in younger and older males and females. Microvascular function was assessed with reactive hyperemia using the microvascular function index (MFI) technique (5mins …

    york Repository record for Resting Microvascular and Autonomic Function in Relation to Age and Sex Hormone Concentrations (opens in a new tab)

  3. The Association Between Sex Hormone Binding Globulin And C-Reactive Protein Levels in Premenopausal Women

    … remains regarding the effect of female sex hormones on the immune system and inflammation process. Sex Hormone Binding Globulin (SHBG) modulates the relative effects of estrogen and testosterone, specifically promoting estrogen effects systemically. Furthermore, estrogen enhances the …

    utmb Repository record for The Association Between Sex Hormone Binding Globulin And C-Reactive Protein Levels in Premenopausal Women (opens in a new tab)

  4. Circulating sex hormone levels in rats: a systematic analysis of the literature and perinatal BPA study

    … or progesterone (P4) levels, according to rat sex and age. We found that estradiol and testosterone, but not progesterone, were different depending on rat strain, which could possibly point to inherent differences in the hormonal regulatory systems between strains, and also potential …

    uiuc Repository record for Circulating sex hormone levels in rats: a systematic analysis of the literature and perinatal BPA study (opens in a new tab)

  5. Association of baseline sex hormone levels and prevalent and incident peripheral arterial disease in the Multi-Ethnic Study of Atherosclerosis

    … the role of endogenous and exogenous sex hormones (including estrogen and testosterone) in the development and treatment of cardiovascular diseases is being examined. In this thesis we evaluate the association between baseline endogenous sex hormone levels and peripheral arterial …

    wfu Repository record for Association of baseline sex hormone levels and prevalent and incident peripheral arterial disease in the Multi-Ethnic Study of Atherosclerosis (opens in a new tab)

  6. Imaging Prostate Cancer: Design, Synthesis, and in Vivo Testing of Steroidal and Non-Steroidal Androgen Selective PET Radiopharmaceuticals

    … to the cellular AR transcription mechanism. Sex hormone binding globulin (SHBG) binds testosterone, the principal circulating androgen, in high affinity and is believed to be directly involved in delivery of the hormone to cytoplasmic AR. Other high-affinity AR compounds, such as …

    uiuc Repository record for Imaging Prostate Cancer: Design, Synthesis, and in Vivo Testing of Steroidal and Non-Steroidal Androgen Selective PET Radiopharmaceuticals (opens in a new tab)

  7. Psycho-endocrinological aspects in aging males and transsexual persons

    Studies on the relationship between behaviour and sex steroids do not always provide consistent results. The aim of this thesis is to contribute to the clarification of certain endocrinological and psychoendocrinological aspects in two different clinical contexts. More subtle changes in androgen …

    ghent Repository record for Psycho-endocrinological aspects in aging males and transsexual persons (opens in a new tab)

  8. Comparison on metabolic markers and hormone level according to serum 25-hydroxyvitamin D level

    … diverse effects on various metabolic markers and hormone. We investigated multiple roles of vitamin D by comparing metabolic markers and hormone levels according to serum 25-hydroxyvitamin D level. METHODS: We investigated 3,399 women who had periodic health examination in Ajou university hospital …

    ajou Repository record for Comparison on metabolic markers and hormone level according to serum 25-hydroxyvitamin D level (opens in a new tab)

  9. Studies on the influence of sex hormones on glucose tolerance and insulin secretion in the rat

    … certain aspects of the general hypothesis that 'sex hormones participate in the physiological regulation of carbohydrate metabolism'. Studies in female rats at different stages of the oestrous cycle, following ovariectomy and during advancing age indicate that enhanced sexual endocrine function …

    aston Repository record for Studies on the influence of sex hormones on glucose tolerance and insulin secretion in the rat (opens in a new tab)

  10. Early Life Determinants of Metabolic and Reproductive Health

    … suggested that childhood obesity and lifetime sex hormone exposure may act as key mediating factors in this relationship. As the prevalence of obesity continues to rise globally and consequent comorbidities place an increasing burden on healthcare systems, understanding the mechanisms that link …

    cambridge Repository record for Early Life Determinants of Metabolic and Reproductive Health (opens in a new tab)

  11. The effects of oestradiol administration on energy metabolism during prolonged exercise in amenorrheic athletes

    … glycogen depletion. Oestradiol (the female sex hormone) has been shown to increase muscle glycogen content at rest and increase the availability of fats as a fuel source during exercise therefore delaying the onset of fatigue. The effects of oestradiol administration on energy metabolism …

    vu-aus Repository record for The effects of oestradiol administration on energy metabolism during prolonged exercise in amenorrheic athletes (opens in a new tab)

  12. The role of fibrolast-derived cytokines on melasma

    … is developed or aggravated by UV radiation, sex hormone, and genetic predisposing factors, however, the exact mechanism of pathogenesis is not clearly demonstrated. Previous studies have been bringing focus into the pigmentation formed by interaction between keratinocytes and melanocytes. …

    ajou Repository record for The role of fibrolast-derived cytokines on melasma (opens in a new tab)

  13. The Vascular Characteristics

    … is developed or aggravated by UV radiation, sex hormone, and genetic predisposing factors, however the exact mechanism of pathogenesis is not yet fully understood. Previous studies indicated that dermal environment such as fibroblasts may have an important role on the development of melasma. …

    ajou Repository record for The Vascular Characteristics (opens in a new tab)

  14. SYNTHESIS OF PHARMACOLOGICALLY ACTIVE MOLECULES THROUGH BIOCATALYTIC APPROACHES: STUDY OF THEIR STEREOCHEMISTRY AND POLYMORPHISM BY MEANS OF SPECTROSCOPIC AND CRYSTALLOGRAPHIC METHODS.

    … non-peptide orally active gonadotropin-releasing hormone (GnRH) antagonist, approved for the treatment of sex hormone-dependent diseases, such as endometriosis and uterine fibroids. This PhD project was focused on this drug, studying its conformational features, and improving the synthetic …

    milano Repository record for SYNTHESIS OF PHARMACOLOGICALLY ACTIVE MOLECULES THROUGH BIOCATALYTIC APPROACHES: STUDY OF THEIR STEREOCHEMISTRY AND POLYMORPHISM BY MEANS OF SPECTROSCOPIC AND CRYSTALLOGRAPHIC METHODS. (opens in a new tab)

  15. Reproductive Biology of the Bonnethead (Sphyrna tiburo) from the Southeastern U.S. Atlantic Coast

    … fecundity. This was accomplished by examining sexually mature male and female bonnetheads, collected monthly (2012-2014) from South Carolina, Georgia, and Florida waters, and monitoring changes in reproductive tract morphology. Changes reflected a seasonal reproductive cycle with an annual …

    unf Repository record for Reproductive Biology of the Bonnethead (Sphyrna tiburo) from the Southeastern U.S. Atlantic Coast (opens in a new tab)

  16. Anthropometric measurements, sexual development and serum reproductive hormonal levels among boys in the rural Western Cape

    … the anthrop ometric growth and reproductive hormones alternation of Western Cape Rural boys who are potentially exposed to agricultural pesticides. Methods: A cross-sectional study of 269 boys was conducted in the rural Western Cape in South Africa. Tests included serum gonadotrophin …

    cape-town Repository record for Anthropometric measurements, sexual development and serum reproductive hormonal levels among boys in the rural Western Cape (opens in a new tab)

  17. The effects of fluctuations in oestrogen and progesterone during the menstrual cycle on glucose homeostasis, energy balance, exercise and premenstrual syndrome

    It is widely accepted that the loss of sex hormones after the menopause is strongly linked with cancer, insulin resistance and obesity, with variations in sex hormone concentrations being responsible in part, for the differences reported in energy metabolism and glycaemic control between genders. …

    oxford-brookes Repository record for The effects of fluctuations in oestrogen and progesterone during the menstrual cycle on glucose homeostasis, energy balance, exercise and premenstrual syndrome (opens in a new tab)

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