Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"sex dimorphism"”.
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Cystatin C and sex dimorphism in experimental autoimmune encephalomyelitis
… role in female but not male EAE mice. This sex dimorphism in the function of CysC could also be observed in immune cell infiltration and demyelination in EAE. Towards elucidating the cellular mechanism(s) underlying the sex difference driven by CysC in EAE, I discovered that the protease …
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Sex dimorphism in the cardiometabolic effects of the smoothelin-like 1 protein deletion in an ageing mouse model
… and diastolic function with increasing age in a sex-dependent manner. The SMTNL1 KO model for the first time recapitulates the sex dimorphic onset of diastolic dysfunction that is central to heart failure with preserved ejection fraction (HFpEF) condition and represents a novel preclinical model …
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Correlated response and sexual dimorphism in bidirectional selection experiments
… traits, and (2) the study of the inheritance of sexual dimorphism or body weight. The first experiment included data from four generations of double two-way selection for body weight and breast angle at eight weeks of age. Breast angle was considered a correlated trait in the weight subpopulation …
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Dental evidence for the peopling of Guam
… tooth crown traits. Chi-square tests for sex dimorphism do not indicate significant differences between males and females. Observer error was found for two traits on the upper first molar and one on the upper canine; The Chamorro dentition exhibits a simplified crown morphology typical of …
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Effect of Maternal Hypoxia on Fetal Development: Programming of HIE Phenotype in Neonatal Rat Brain
… observed in the kidneys of the adult rats in a sex dimorphism way, affecting more the females than the males. In addition, we observed that maternal hypoxia increased the vulnerability of the brain to HIE on P-10 pups by repressing the expression of GR. Epigenetics studies demonstrated that this …
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An integrated multi-omics approach to improve our understanding of ageing and neurodegeneration
… activated across age. This activation also shows sex dimorphism, that we also identified by differential expression of 26 X-chromosome associated genes across age. Our co-expression analysis suggested that many gene modules are preserved across age, except during the young age (20-35 years of age) …
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Estrogen Signaling in the Ventromedial Hypothalamus Modulates Adipose Tissue Metabolic Adaptation
… of the ventromedial hypothalamus (vlVMH), a sex-dimorphic structure that directly modulates brown adipose tissue (BAT) thermogenesis. We previously showed that an ERαvlVMH-originated neural circuit responds to changes in ambient temperature and nutritional states, suggesting a potential role …
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Environmental and Genetic Factors Affecting Bone Diseases and Phenotypes in Mouse Models
… of disease.</p> <p>In addition, we examined the sex differences in several mouse models of inflammatory arthritis. To understand the basis for these differences we conducted analysis of several mouse models of inflammatory arthritis. The study of whether there are gender and symmetry differences …