Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 24 for “"severe sepsis"”.
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Reducing Mortality from Severe Sepsis and Septic Shock: A Macro System Approach
… tying financial reimbursement to improvement of sepsis outcomes. For success to be achieved, organizations should partner with prehospital providers to improve sepsis care, similar to partnerships which have historically improved acute myocardial infarction and stroke care within communities. …
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Pre and Post Implementation Evaluation of an Emergency Department Severe Sepsis Alert and Practice Protocol
Severe sepsis kills an estimated 1,400 people worldwide every day. This often fatal infectious process accounts for an estimated 215,000 deaths in the United States (US) annually. The main goal of this project was to evaluate the impact of the Emergency Department Severe Sepsis Alert and Practice …
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The Role of Arginine Vasopressin Receptor 2 in Microvascular Hyperpermeability During Severe Sepsis and Septic Shock
Sepsis compromises more than 18 million lives worldwide every year. Moreover, methicillin-resistant Staphylococcus aureus (MRSA) sepsis is one of the most severe types. Despite efforts to provide novel therapies for sepsis, the mortality has not decreased in several decades. Sepsis often leads to …
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Associatioin of severe anaemia with tuberculosis mycobacteraemia in HIV positive patients admitted with severe sepsis to the University Teaching Hospital, Lusaka,Zambia
… is recognised as one the leading causes of severe sepsis among HIV positive patients. Most patients with tuberculosis mycobacteraemia have advanced HIV disease with CD4 counts less than 100cells/ul and many do not present with the classical signs of tuberculosis. Unusual presentation of …
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Association of severe anaemia with tuberculosis mycobacteraemia in HIV positive patients admitted with severe sepsis to the University Teaching Hospital, Lusaka,Zambia
… is recognised as one the leading causes of severe sepsis among HIV positive patients. Most patients with tuberculosis mycobacteraemia have advanced HIV disease with CD4 counts less than 100cells/ul and many do not present with the classical signs of tuberculosis. Unusual presentation of …
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Associatioin of severe anaemia with tuberculosis mycobacteraemia in HIV positive patients admitted with severe sepsis to the University Teaching Hospital, Lusaka,Zambia
… is recognised as one the leading causes of severe sepsis among HIV positive patients. Most patients with tuberculosis mycobacteraemia have advanced HIV disease with CD4 counts less than 100cells/ul and many do not present with the classical signs of tuberculosis. Unusual presentation of …
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Identifying and Assessing Barriers to Meeting Sepsis Guidelines in the Emergency Department at an Urban Academic Medical Center: A Process Analysis
Problem: Globally, sepsis is a major public health problem with 48.9 million cases worldwide in 2017; the United States experiences 1.7 million cases annually that significantly contribute to patient morbidity and mortality. Timely recognition and management of sepsis, especially in the emergency …
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Outcomes after Apheresis in patients with underlying Heart Failure: A Propensity Matched National Cohort Analysis
… disturbances, coagulation abnormalities, and severe sepsis. Results: Apheresis in patients with HF had a higher percentage of in-hospital mortality, acute kidney injury, major bleeding, cardiogenic shock, mechanical circulatory support, mechanical ventilation, calcium abnormalities, fluid and …
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Host response in sepsis
Sepsis is a serious condition characterized by a systemic inflammatory response to an infection. Increased vascular leakage, vasodilation and heart failure cause circulatory disturbances challenging the intensivist. Despite modern medication and high technology supportive care, mortality is high. …
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Why, how and when do children die in a Paediatric Intensive Care Unit (PICU) in South Africa?
… after-hours periods (45.5% vs. 54%; p = 0.07). Severe sepsis (21.9%) was the most common condition associated with death, followed by cardiac disease (18.6%).Ninety-four (20.8%) patients were readmitted to the PICU within the same year; 278 (61.6%) had complex chronic disorders. During the last …
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INTERDEPENDENT REGULATION OF METABOLISM AND INFLAMMATION IN HUMAN MONOCYTES
Sepsis is serious medical condition which kills millions of people worldwide each year. In the United States, severe sepsis has a mortality rate of 20-30%, with an annual cost of over $25 billion. Modern advances in supportive care have brought the mortality rate down to its current level, however …
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"A syndrome so characteristic" Molecular and clinical studies of Fusobacterium necrophorum and Lemierre's syndrome
… patients with Lemierre’s syndrome were severely ill, in a majority fulfilling the criteria for severe sepsis. Underlying thrombophilia was not over-represented in patients with Lemierre’s syndrome and concomitant EBV infection was uncommon. Finally, we found that the gene coding for …
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Circulating proteoglycans and glycosaminoglycans during critical illness
… wall. All these functions are disturbed during severe sepsis. The present thesis aims at determining if these molecules are increased in concentration of septic patients and/or if the blood levels provide additional information useful in the management of these patients. We found that …
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Nursing Perspectives and Opinions on Early or Delayed Sepsis Treatment: A Mixed Methods Approach
… at least 1.7 million adults in America develop sepsis. Sepsis can lead to life threatening organ dysfunction, severe hypotension, and death when severe sepsis or septic shock is involved. Sepsis is responsible for 50% of acute kidney injury (AKI), which is the most common form of organ …
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HIV positive patients in intensive care - a retrospective chart review
… P <0.001). Predictors of hospital mortality were severe sepsis on admission (OR, 2.8; 95% CI 0.9 - 9.1;p 0.07), receipt of renal replacement therapy (OR, 1.9; 95% CI 1.0 - 3.6; p 0.056), receipt of inotropic support (OR, 2.0; 95% CI 1.4 - 3.2; p 0.001). Use of highly active antiretroviral therapy, …
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Predictors of Septic Patient Outcomes
… to identify factors and outcomes associated with sepsis management.</p> <p>Conceptual Framework: Two conceptual models: Donabedian’s Model of Healthcare Quality (Donabedian, 1980; 2003) and Advancing Health Disparities Research within the Health Care System Conceptual Framework (Kilbourne, …
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Aspects of sepsis/SIRS - An experimental study on fluid therapy, vitamin C and plasma volume in increased permeability
In sepsis, after major surgery or severe trauma, the human body may suffer from various degrees of generalized inflammation, a syndrome called Systemic Inflammatory Response Syndrome (SIRS). One feature of SIRS is increased capillary permeability, caused by disruption of the capillary endothelium …
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Invasive disease by Haemophilus influenzae in Sweden in the era of the H. influenzae type b vaccine
… a common cause of meningitis, epiglottitis and severe sepsis in young children. In the late 1980’s an effective conjugated vaccine against Hib was developed and a dramatic fall in Hib incidence was observed in countries that implemented vaccination. This includes Sweden, where the vaccine was …
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Die Behandlung der schweren Sepsis bei Peritonitis durch intravenöse Gabe von Taurolin - eine prospektive, kontrollierte, randomisierte Studie
… wurde die adjuvante Therapie der schweren Sepsis bei Peritonitis durch imtravenöse Gabe von Taurolin alleine, Taurolin und Antibiotika, sowie Antibiotika alleine. Primärer Endpunkt war die Krankenhaus-Letalität. Es fand sich kein signifikanter Unterschied, jedoch eine nicht signifikante …
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