Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 16 of 16 for “"severe outcomes"”.
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An Application of the Extended Parallel Process Model to Optimize Health Messages for At-Risk Populations during COVID-19: Investigating the Relationship between Threat Perception and Protective Health Behaviours in People with Obesity
… Obesity (PwO) are at an increased risk of more severe outcomes of COVID-19. Although protective behaviours can reduce the spread of COVID-19, strategies are required to motivate PwO to engage in these behaviours. Targeted messages can be used to encourage adherence to protective behaviours; …
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Characteristics of Patients Who Visit the Emergency Department with Self-inflicted Injury
… attempts were evaluated. Moreover, predictors of severe outcomes were evaluated. A total of 2,996 patients with self-inflicted injuries visited the three centers during a period of 3 years. The male-to-female suicide ratio was 1:1.38 (P < 0.001). The mean age was 41 years. Poisoning was the most …
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The Role of Resilience in Sexual Assault Revictimization
… sexual assaults has been linked with more severe outcomes, specifically post-traumatic stress symptoms (PTSS). Yet, 75% of individuals recover following sexual assault. It is possible that resilience factors may play a crucial role in facilitating recovery. However, relatively little is …
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Trends in Chlamydia trachomatis Treatment Prescribing Practices in King County, Washington, 2010 - 2018
… at higher risk for CT reinfection and subsequent severe outcomes. The differences in prescribing practices by facility and patient characteristics highlight the need for targeted and multifaceted educational campaigns to encourage a transition to doxycycline use.
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The relationship between faecal haemoglobin concentration and risk of significant colorectal neoplasia in screening and symptomatic populations.
… advanced neoplasia compared to those with less severe outcomes (200.0 v. 166.0 µg Hb/g faeces, p < 0.0001). Those with elevated faecal Hb concentration (60.0 - 79.9 µg Hb/g faeces) at the time of a negative test result (< 80.0 µg Hb/g faeces) were more likely to be later diagnosed with an …
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Identifying parasite virulence factors and host genetic and immunologic factors that contribute to severe malarial outcomes in Ugandan children
Cerebral malaria (CM) and severe malarial anemia (SMA) remain drivers of morbidity and mortality due to Plasmodium falciparum infection in children in Sub-Saharan Africa. There are currently no adjunctive therapies for severe malaria (SM), suggesting that we need a better understanding of both host …
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Diabetes and the Female Heart
… diabetic women experiencing disproportionately severe outcomes compared to diabetic men. The mechanisms underlying these sex specific outcomes remain unclear. This thesis investigated how sex and type 2 diabetes interact to influence cardiac mechanics, energetics, and structure, focusing on …
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Mexican-Born Immigrant Decision-Making About Self-Management of Type 2 Diabetes
… sensitivity, rapid prediabetes/T2D onset, and severe outcomes. Ineffectively managed blood glucose (BG) risks serious complications, reduced life quality, and premature death. T2D is primarily self-managed; requiring BG control. HCPs teaching Mexican émigrés encounter culturally-steeped beliefs …
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Rhabdomyolysis-induced Acute Kidney Injury in Sickle Cell Disease
… from rhabdomyolysis-induced AKI and improving outcomes for individuals with SCD. In this project, we demonstrate that transgenic SCD mice (Townes model) are susceptible to glycerol-induced rhabdomyolysis, with a 100% mortality rate within 8-24 hours following intramuscular glycerol injection. …
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The Gut Mucosal Microbiome of HIV- exposed Uninfected Infants in Africa
… has recently been associated with disease outcomes and progression in several disease areas. The microbial colonisation of the infant begins in utero and continues after birth. It is affected by several factors: birth mode, age of gestation, feeding mode, maternal health status as well as …
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Characterization of pro- and anti-inflammatory immune responses in SARS-CoV-2 infection
… go unmitigated or unresolved, resulting in the severe COVID-19 manifestation of the 'cytokine storm,' or multisystem inflammatory syndrome in children (MIS-C). One classically increased protein in cytokine storm of COVID-19 patients is C-X-C motif chemokine 10 (CXCL10), which has been explored …
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Natural Genetic Variants in Humans and Salmonellae Underlie Variable Infection Outcomes
… pandemic highlights, infectious diseases outcomes range from asymptomatic cases to prolonged morbidity and death. We can predict these outcomes using risk factors like age and BMI; however, we currently lack the capacity to generate more fine-grained, or even individualized, outcome …
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Socioeconomic inequalities in COVID-19 outcomes in south Africa
… inequalities associated with COVID-19 outcomes at the district level in South Africa. While previous literature has frequently relied on income as a measure of socioeconomic status, it's essential to recognize that socioeconomic standing is multifaceted and dynamic. In this study, we …
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Serious and Fatal Injury Risk in Road Departure Crashes with Guardrail
… the guardrail face. Cars showed odds of minor to severe injury 3.6 times greater than LTVs in end terminal crashes. End terminal designs compliant with NCHRP 350 were not observed to carry significantly different odds of minor to severe injury than non-compliant end terminals. The findings control …
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Ambulatory and hospitalized childhood pneumonia: a longitudinal study in a peri-urban low-income community with high vaccination coverage in Sub-Saharan Africa
… and identify risk factors for pneumonia and for severe outcomes. Methods A prospective birth cohort, the Drakenstein Child Health Study, enrolled mother-infant pairs in two communities outside Cape Town, South Africa. Pregnant women were recruited and followed through pregnancy, labour and …
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Genetic ancestry and population health: elucidating the relative role of African genetic ancestry in cancer genomics and the broader implications for racial health disparities in cancer
… African Americans, face some of the most severe outcomes, including higher incidence rates, delayed diagnoses, poorer prognoses, reduced survival, and less effective responses to treatment. While historical and systemic inequities in healthcare, as well as socioeconomic factors such as …