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Showing 1 to 3 of 3 for “"serum response element (SRE)"”.

  1. Comparative analysis of the promoters of the CyI-CyIIa-CyIIb actin gene cluster in the sea urchin Strongylocentrotus purpuratus

    … while CyI and CyIIb share an identical CArG (or serum response element) and extensive sequence homology in the upstream region, homology with CyIIa is essentially limited to consensus protein binding sites, including the serum response element (SRE) and an octamer motif. Along with several other …

    wvu Repository record for Comparative analysis of the promoters of the CyI-CyIIa-CyIIb actin gene cluster in the sea urchin Strongylocentrotus purpuratus (opens in a new tab)

  2. Construction of CNFY-CNF1 Chimera Protein for Study of Differential pH Dependent Activity of CNF Proteins

    … as well as direction to begin testing. Using serum response element (SRE) has been seen as an effective way to test cellular activity for PMT and CNFs. In this thesis, we focus on the construction of CNF chimeras so that SRE-based reporter tests may be conducted in future studies.

    uiuc Repository record for Construction of CNFY-CNF1 Chimera Protein for Study of Differential pH Dependent Activity of CNF Proteins (opens in a new tab)

  3. Investigation of the intracellular trafficking pathways of the dermonecrotic toxin family

    … evidenced by inhibition of PMT activity in our SRE-based reporter assay, with nocodazole and cytochalasin D, respectively, suggesting that membrane translocation and cytotoxicity of PMT is dependent on its transfer to late endosomal compartments. In contrast, disruption of Golgi-endoplasmic …

    uiuc Repository record for Investigation of the intracellular trafficking pathways of the dermonecrotic toxin family (opens in a new tab)