Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"serum response element"”.
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Comparative analysis of the promoters of the CyI-CyIIa-CyIIb actin gene cluster in the sea urchin Strongylocentrotus purpuratus
… while CyI and CyIIb share an identical CArG (or serum response element) and extensive sequence homology in the upstream region, homology with CyIIa is essentially limited to consensus protein binding sites, including the serum response element (SRE) and an octamer motif. Along with several other …
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Construction of CNFY-CNF1 Chimera Protein for Study of Differential pH Dependent Activity of CNF Proteins
… as well as direction to begin testing. Using serum response element (SRE) has been seen as an effective way to test cellular activity for PMT and CNFs. In this thesis, we focus on the construction of CNF chimeras so that SRE-based reporter tests may be conducted in future studies.
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Erforschung des Beitrags des MAPK- und STAT-Signalwegs an der EGF-vermittelten Aktivierung der c-fos-Gen-Expression
… in seiner Promotor-Region. Diese Promotor-Elemente sind entscheidend an der spezifischen Antwort zu verschiedenen Umweltreizen, denen Zellen im Körper ausgesetzt sind, beteiligt. Die Stärke der c-fos-Gen-Expression ist abhängig von den, in der Promotor-Region-gebundenen …
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Estrogen action in the myocardium
… of an estrogen target gene, the early growth response gene-1 (Egr-1) and 3) to initiate the search for novel estrogen target genes in the myocardium. 1) The effects of estrogen on the expression of one of the major myocardial specific contractile proteins, the alpha-myosin heavy chain …
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Investigation of the intracellular trafficking pathways of the dermonecrotic toxin family
… highest SRE activation. DNT elicited minimal SRE response, presumably due to paucity of DNT cellsurface receptors on HEK 293T/17. It has been previously demonstrated that the CNFs are dependent upon endosomal acidification for translocation into the cytosol. The results reported herein demonstrate …