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Showing 1 to 20 of 20 for “"serum amyloid A"”.
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Equine Septic Arthritis and Serum Amyloid A
… quantify the major equine acute phase protein, serum amyloid A (SAA) may fulfill this need. Serum amyloid A increases in the body in response to injury, infection, and inflammation and shows promise as a useful tool in confirming a diagnosis of sepsis, as inflammation causes mild increases in …
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SERUM AMYLOID A IN RUMINANTS: DIAGNOSTIC VALUE AND FOOD CONTAMINATION ASSESSMENT
… to investigate the bovine acute phase protein Serum Amyloid A, focussing on its value as safety marker in farm animals. SAA can be considered as a natural anti-inflammatory and immunomodulatory agent and local expression of SAA, at the site of the initial acute phase reaction, could protect …
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Epithelial Retinoic Acid Receptor Beta Regulates Serum Amyloid A Expression and Vitamin A-Dependent Intestinal Immunity
… RARβ activated vitamin A-dependent expression of serum amyloid A (SAA) proteins by binding directly to Saa promoters. In accordance with the known role of SAAs in regulating Th17 cell effector function, epithelial RARβ promoted IL-17 production by intestinal Th17 cells. More broadly, epithelial …
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Clinical utility of serum amyloid A to differentiate feline disease processes using a newly validated point of care assay
DSpace SAF Submission Ingestion Package generated from Vireo submission #17965 on 2022-11-14 at 17:34:07
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The effects of equine plasma transfusion on markers of inflammation in healthy neonatal foals
… in acute phase protein (fibrinogen [FIB] and serum amyloid A [SAA]) production. A total of 35 healthy, neonatal foals (mean ± SD age 34 ± 5 hours) were randomly allocated into one of two groups, and given either hyperimmune, fresh frozen plasma (treatment) or crystalloids (control) by IV …
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Migrena sergančių moterų ląstelinės hemostazės ir periferinių kraujagyslių kitimai /
… registered in the M0 group. The relation between serum amyloid A, C reactive proteine and types of migraine, changes in functional activity of platelets and changes in functionality or stiffness of endothelium of peripheral blood vessels of various diameter was not proved. Women with migraine had …
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Maternal body mass index and proinflammatory immune markers in HIV-infected pregnant woman on antiretroviral treatment in Cape Town, South Africa
… inducible protein-10 (IP-10) and serum amyloid A (SAA)) and maternal weight measured from April 2015 to October 2016, at four antenatal care visits (visit 1, 2 (two weeks post-ART initiation in those initiating in pregnancy), 3 and 4). The association with maternal BMI by ART …
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Hypoxic Influences On Myeloid Cells During Inflammation And Inflammation-Associated Cancer
… pro-resolving phenotype, and elevates gut serum amyloid A levels during the resolution phase of colitis. These data suggest that myeloid HIF signaling promotes the effective resolution of acute colitis. Second, the effect of HIF inhibition in colitis-associated cancer (CAC) and other …
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HEPATOCYTES COORDINATE A SYSTEMIC ENDOCRINE NETWORK IN CANCER
… hepatocyte-derived acute phase reactants serum amyloid A proteins 1 & 2 (SAA) as key determinants of liver directed inflammation. Genetic ablation of SAA receptor toll-like receptor 2 (TLR2) or the TLR signaling adaptor MyD88 reversed these microenvironmental changes in the liver. Notably, …
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Rheumatoide Arthritis: Proteomische Analyse von Serum und synovialen Fibroblasten zur Detektion von Biomarkern
… Im zweiten, globalen Ansatz wurde humanes Serum durch Differenzielle-In-Gel-Elektrophorese (2D-DIGE) untersucht. Zuvor wurden high abundand Proteine durch den Einsatz einer MARC (multiple affinity removal column) abgereichert, um die low abundand Proteine besser visualisieren zu können. …
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Investigating biomarkers in clinical samples that are predictive of response in multiple myeloma
… treatment. Proteomic analysis was performed on serum samples collected prior to treatment from 39 newly-diagnosed multiple myeloma patients receiving thalidomide-based regimens (22 responders; 17 non-responders). Serum samples were initially immunodepleted to enrich for low-abundance proteins, …
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Analytical validation and evaluation of the effects of intramuscular injections on acute phase proteins in horses
… of selected APP, including fibrinogen (FIB), serum amyloid A (SAA), and HAP, as well as on the activity of selected enzymes, including creatine kinase (CK) and aspartate aminotransferase (AST). The plasma concentrations of the aforementioned variables were evaluated for 5 consecutive days …
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Physiological and Biochemical Aspects of Methionine Isomers and Precursors in Broilers
… decreased the level of acute phase protein serum amyloid A compared to the control group (P > 0.05). The effect of Met supplementation on gene expression of nutrient transporters and Met converting enzymes were complex and dynamic. Most of the target genes demonstrated tissue- and …
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Effects of Lipopolysaccharide Induced Inflammatory Response on Early Embryo Survival in Ewes
… acute phase proteins (APP), haptoglobin (Hp) and serum amyloid A (SAA), were initiated to study their effects on embryonic loss. In addition, ewes were also injected with LPS plus dexamethasone (Dex) to study its effects on indirectly altering embryonic loss through toll-like receptor 4 (TLR4). …
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Serum Lipocalin-2 (LCN-2) as a major acute phase protein under different pathological conditions in vivo and in vitro studies
… Nierenschäden und Entzündungen eingesetzt. Sein Serumspiegel unter verschiedenen pathologischen Bedingungen erhöht, aber die Quelle und Ursache sind unklar. Das Ziel unserer Studie war es, zur prospektiven Evaluierung der LCN-2-Expression in verschiedenen pathologischen Zuständen. Das Ziel …
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Effects of a blend of green tea and curcuma extract supplementation on lipopolysaccharide-induced inflammation in horses and ponies
… In allen Blutproben wurden die Parameter Serum Amyloid A (SAA), Haptoglobin (Hp) und Retinol-bindendes Protein 4 (RBP4) gemessen. Mittels RT-qPCR wurden in allen Leberbioptaten die mRNA-Level ausgewählter Entzündungsmarker bestimmt (Hp, TNF-α, IL-1β, IL-6, CD68, FGF21, NF-kB, ATF4). …
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Influence of body weight gain on insulin regulation, adipose tissue inflammation and lipid metabolism in equines
… Glucose was analysed in natrium fluoride plasma. Serum amyloid A (SAA), insulin, non-esterified fatty acids (NEFA) and triglycerides were measured in serum. Levels of inflammatory parameters (CD68, IL-1β, IL-6, TNFα) and markers of lipid metabolism (FABP4, LPL) were analyzed in AT samples by …
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The effects of feeding a negative dietary cation-anion difference diet at two dietary calcium inclusion rates to close up dry cows on the subsequent lactation uterine health and fertility
… as markers of oxidative stress. Blood plasma and serum samples were harvested at -28, -21, -14, -7, 15 and 30 DIM and were assessed for concentrations of lipopolysaccharide binding protein (LBP), serum amyloid A (SAA) and haptoglobin (HP). Ovarian dynamics was assessed at 7, 9, 11-17, 20, 30, 55, …
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TUMOR PROMOTING FUNCTIONS FOR THE METABOLIC REGULATOR SIRT5
… inflammation. Among these dysregulated genes, serum amyloid A (Saa), a gene that encodes for an acute phase protein linked to inflammation, was significantly downregulated in Sirt5-/- PyMT mammary tumors. Increased levels of SAA have been linked to tumor pathogenesis and metastasis. In light of …
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REGULATION AND EXPRESSION OF AMYLOID CURLI IN SALMONELLA INFECTION
… and extracellular DNA. Curli are functional amyloids with a rich β-sheet structure strikingly similar to pathological and immunomodulatory human amyloids such as β-amyloid, α-synuclein, and serum amyloid A. It is often debated if enteric bacteria express curli and form biofilms in the gut …