Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"sequence polymorphisms"”.
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Mitochondrial DNA Control Region Sequence Polymorphisms from a South Indian Population Sample: A Forensic and Phylogenetic View
… individuals residing in Tamil Nadu, India were sequenced. A total of 57 haplotypes were observed of which 55 were unique. The Tamil Nadu population sample was characterized by high genetic diversity (0.9977), low random match probability (1.90%), and moderate average number of pairwise …
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Exploring the association between gene sequence polymorphisms within the angiogenesis and extracellular matrix regulatory pathways and shoulder pain and disability following breast cancer treatment
Shoulder pain and disability are common sequelae of breast cancer treatment in women, with an understated negative impact on the quality of life of affected individuals and a poorly characterised aetiology. A better understanding of the aetiology of shoulder pain and disability in breast cancer …
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Genetic diversity of the HvFT1 flowering gene in Nordic spring barley (Hordeum vulgare L.)
… of the HvFT1 gene in Nordic spring barley. Sequence variation in this gene is known to influence flowering time in some barley varieties and my aim is to determine whether genetic diversity in HvFT1 contributes to known flowering time differences in Nordic barley lines. To that end, …
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Cloning and characterization of AdeMNO RND efflux pump of Acinetobacter baumannii
… of isolates. The adeMNO operon was cloned, sequenced, and characterized using the single copy gene expression system in an efflux sensitized surrogate Pseudomonas aeruginosa strain. Antibiotics, trimethoprim, chloramphenicol, and clindamicin were identified as the substrates of this pump. In …
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Functional Analysis of Genomic Variation and Impact on Molecular and Higher Order Phenotypes
… study functions of thousands of normal sequence variants and spontaneous mutations that segregate in intercross and backcross progeny generated by mating completely sequenced parental lines. To evaluate this new reverse genetic method we resequenced the genome of one of the oldest inbred …
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The role of heterodera glycines biotin synthase in the nematode-soybean interactions
… H. glycines biotin synthase (HgBioB), contained sequence polymorphisms between avirulent and virulent inbred SCN strains. To test the function of avirulent and virulent HgBioB alleles, a complementation experiment using mutant Escherichia coli with these two HgBioB alleles was conducted. Here we …
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Characterization of two component systems of Acinetobacter baumannii.
… TCSs operons in AB030 and AB031 also identified sequence polymorphisms that could alter the activities of these TCSs in AB030 and AB031. Finally, we identified A1S_3229_30 an excellent candidate that may act as global regulator of antibiotic and virulence in A. baumannii. The sequence of …
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Genetic determinants of NEIL2 transcription
… NEIL2 transcription, including cis-regulatory sequences and sequence polymorphisms, were unknown. We hypothesize that cis-regulatory sequences in the 5’ upstream region of NEIL2 regulate gene transcript levels and that SNPs proximal to these sequences impact gene regulation and thus affect DNA …
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Development of Computational Tools and Resources for Cotton microRNA Analysis
… between cotton and other plant species, sequence polymorphisms, expressed miRNAs and their targets, and SSR analysis. A total of 27,956 indel mutants and 149,616 single nucleotide polymorphisms (SNPs) were identified from consensus contigs. In a comparison with six model plant species, …
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Population genetic frameworks and functional genomics of Mycobacterium bovis
… bovis phylogeny. Genome-wide single nucleotide polymorphisms (SNPs) studies in M. tuberculosis have shown sufficient resolution to develop trait-allele associations. We hypothesized that genetic and phenotypic diversity in M. bovis is enciphered in their genomes. To study genetic variations we …