Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"septation"”.
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An Illustrative Approach to Understanding the Developmental Processes of Atrial and Ventricular Septation of the Heart During Embryogenesis and How Errors in These Processes Lead to Congenital Septal Heart Defects
… processes of atrial and ventricular septation, as well as the abnormal development of these processes that result in both atrial and ventricular septal defects. The use of animation, as opposed to two-dimensional illustrations, will possibly increase understanding of these subjects …
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Investigation into the antimicrobial activity of cationic antibacterials.
… of minimal K+ loss in all bacterial species; non-septation and aggregation in all test species. Colistin use was abandoned clinically between 1970-2000 and is not used clinically against Gram-positive species. Colistin exposure induced a common response from test bacteria including the …
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Novel Non-Repulsive Outcomes From Ephrin-B Reverse Signaling
… signals present with defects in urorectal septation of the hindgut, tubularization of the urethra, tracheoesophageal septation of the foregut, closure of the palatal shelves, and closure of the embryonic eyelid, defining roles for ephrin-B2 reverse signaling in each of these developmental …
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Role of the Aspartyl Protease SpoIIGA in the Compartmentalization of Sigma Factor Activation During Sporulation of Bacillus subtilis
… for σE compartmentalization suggests that before septation SpoIIGA is evenly distributed throughout the entire cell membrane. Once septation occurs, there is a higher amount of SpoIIGA in the mother cell than in the prespore. SpoIIGA is then concentrated in the septum and the mother cell …
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Characterisation of the role of Sox4 in mouse embryonic development
… null and conditional null mutant alleles exhibit septation defects, oedema, and lethality by E14.5. However, the causative step in development, where a loss of functional Sox4 marks the beginning of the defect, has not been described; nor has it been uncovered whether mutation to Sox4 results in …
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Discovery of novel antibacterial and antitubercular compounds using chemical genetics and computational approach targeted at phospholipid biosynthesis
… of S. coelicolor (i.e. hyphal growth, branching, septation and sporulation) therefore verified the potential of these proteins as drug targets. Although, the early stage "hit identification" approach using a modest collection of compounds was unsuccessful, further screening of relevant compounds …
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Zebrafish Cardiac Development Requires a Conserved Secondary Heart Field
<p>Despite its lack of septation, the tissue patterning of the arterial pole of the zebrafish is remarkably similar to the patterning of pulmonary and aortic arterial poles observed in mouse and chick. The secondary heart field (SHF) is a conserved developmental domain in avian and mammalian …
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Bipolaris zeicola: physiological races, morphology and resistance on maize
Conidial length, width, septation, curvature and pigmentation of 39 isolates of Bipolaris zeicola (Stout) Shoemaker from different geographical areas and representing distinct physiological races were examined. Wide variability in conidial morphology was found among isolates of each race. No …
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Determinants Influencing Polar Flagellar Biosynthesis and Cell Division in Campylobacter jejuni
… spatially prevent polar division and encourage septation at the cellular midpoint for symmetrical division. This work greatly extends our understanding of factors that govern spatial and numerical patterns of polar flagellation and has identified an unprecedented system to spatially regulate …
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Periplasmic determinants of virulence in Salmonella enterica
… of three proteins involved in cell septation: AmiA, AmiC, and SufI.
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BUBR1 in Cardiac Biology: From Cardiogenesis to Adult Heart Function and Aging
… with severe defects in chamber wall formation, septation, and trabeculation. Single-cell RNA sequencing analysis revealed disrupted differentiation trajectories, suppressed cardiogenesis genes, and hyperactivation of Wnt signaling in cardiac specific BubR1 knockout embryonic hearts, underscoring …
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The chemotaxonomy of the fungal genus Endothia fr.
… based on differences in ascospore shape and septation, stromatic configuration and distribution of stromatic tissues. This group of fungi traditionally contains some important plant pathogens; its taxonomic position needs to be resolved. The morphological criteria used by Barr were …
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Automated hydrodynamic trap for single cell analysis in free solution
… Oscillospira spp. These bacterium have distinct septation patterns and form spores. In particular, O. guilliermondii has been observed in these rumen sample for almost a century yet we are still unable to cultivate them within the lab. Our hydrodynamic trapping technique was able to isolate and …
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Cell physiology based pharmacodynamic modeling of antimicrobial drug combinations
… We used this representation to describe septation dynamics during the transition of a bacterial culture from the exponential to stationary growth phase. Resulting from a new mechanistic understanding of transition processes, we explained the lag time between the increase in cell number …
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Biochemical, structural and functional analysis of the cell division site determinant MinD(Ng): To divide or not to divide
… MinC, to the membrane where it prevents septation. Counteracting this effect is MinE which can bind to MinD, thereby displacing MinC. Formation of the MinE-MinD complex also stimulates the ATPase activity of MinD, and is required for the periodic oscillations of the MinC-MinD complex on …
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How the Heart Grows: From Multi-scale Data to a Multi-scale Model
… heart. The looping phase is then followed by septation and valve formation giving rise to a four chambered heart in avians and mammals. The looping phase plays a central role in heart development. Successful looping is essential for proper alignment of the future cardiac chambers and tracts. …
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Characterization of ftsA conditional lethal mutants shows that FtsA is required at early and late stages of cell division in Streptococcus pneumoniae
… a target to develop novel inhibitors active on septation. Moreover, the data suggest that an early block in cell division in S. pneumoniae impairs both growth and division, supporting a model in which a single machinery, containing both complexes, one for peripheral elongation and one for septum …
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Regulation of septum formation by RHO4 GTPase signalling in Neurospora crassa
Zytokinese bezeichnet den Prozess, bei dem eine einzelne Zelle in zwei Tochterzellen geteilt wird, und ist bei Eukaryoten hoch konserviert. Die Rho GTPasen sind in ihrer Funktion als Schlüsselregulatoren zahlreicher zellulärer Prozesse auch wesentlich an der Zellteilung beteiligt. Über die genauen …